Pub. Date : 2001 May
PMID : 11378569
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have identified activating mutations of c-kit at codon 816 (Asp(816) ) from a revertant of the cytokine-dependent acute myeloid leukemia (AML) cell line, MO7e (D816H), and de novo childhood AML (D816N). | Aspartic Acid | KIT proto-oncogene, receptor tyrosine kinase | Homo sapiens |
| 2 | These results suggest a potentially important role of Asp(816) mutations of c-kit in both malignant cell proliferation and resistance to therapy. | Aspartic Acid | KIT proto-oncogene, receptor tyrosine kinase | Homo sapiens |