N-Acetylneuraminic Acid

cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene ; Homo sapiens







34 Article(s)
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1 34294193 Serum Antibodies to N-Glycolylneuraminic Acid Are Elevated in Duchenne Muscular Dystrophy and Correlate with Increased Disease Pathology in Cmah-/-mdx Mice. 2021 Aug 2
2 34587757 Dietary Neu5Ac Intervention Protects Against Atherosclerosis Associated With Human-Like Neu5Gc Loss-Brief Report. 2021 Nov 2
3 32556248 Multiple Genomic Events Altering Hominin SIGLEC Biology and Innate Immunity Predated the Common Ancestor of Humans and Archaic Hominins. 2020 Jul 1 2
4 32664459 Gram-Negative Bacterial Endotoxin LPS Induces NeuGc Loss through Ets1-Dependent Downregulation of Intestine-Specific pcmah Transcript in Porcine Intestinal Cells. 2020 Jul 10 2
5 30616506 Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype of human lymphocytes and sensitivity to HIV-1 infection. 2019 Jan 7 1
6 31134048 Absence of Neu5Gc and Presence of Anti-Neu5Gc Antibodies in Humans-An Evolutionary Perspective. 2019 1
7 31289278 Antitumor effects of the GM3(Neu5Gc) ganglioside-specific humanized antibody 14F7hT against Cmah-transfected cancer cells. 2019 Jul 9 1
8 31332008 Human species-specific loss of CMP-N-acetylneuraminic acid hydroxylase enhances atherosclerosis via intrinsic and extrinsic mechanisms. 2019 Aug 6 1
9 31628314 Sialic acid mediated mechanical activation of β2 adrenergic receptors by bacterial pili. 2019 Oct 18 1
10 31681287 N-Glycolylneuraminic Acid (Neu5Gc) Null Large Animals by Targeting the CMP-Neu5Gc Hydroxylase (CMAH). 2019 4
11 29206915 Phylogenetic Distribution of CMP-Neu5Ac Hydroxylase (CMAH), the Enzyme Synthetizing the Proinflammatory Human Xenoantigen Neu5Gc. 2018 Jan 1 1
12 30564250 Possible Influences of Endogenous and Exogenous Ligands on the Evolution of Human Siglecs. 2018 1
13 28049733 Physiological Exploration of the Long Term Evolutionary Selection against Expression of N-Glycolylneuraminic Acid in the Brain. 2017 Feb 17 2
14 28423240 Biochemical, Cellular, Physiological, and Pathological Consequences of Human Loss of N-Glycolylneuraminic Acid. 2017 Jul 4 2
15 28893995 N-glycolyl groups of nonhuman chondroitin sulfates survive in ancient fossils. 2017 Sep 26 1
16 27041489 Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite. 2016 Apr 4 2
17 27567275 Natural anti-carbohydrate antibodies contributing to evolutionary survival of primates in viral epidemics? 2016 Nov 2
18 27593514 Streptococcus pneumoniae Senses a Human-like Sialic Acid Profile via the Response Regulator CiaR. 2016 Sep 14 8
19 26235586 Production and Purification of Secretory Simian Cytidine Monophosphate-N-acetylneuraminic Acid Hydroxylase Using Baculovirus-Protein Expression System. 2015 1
20 25480294 Host adaptation of a bacterial toxin from the human pathogen Salmonella Typhi. 2014 Dec 4 2
21 25517696 Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors. 2014 Dec 17 2
22 23709682 Enhanced T cell function in a mouse model of human glycosylation. 2013 Jul 1 2
23 21350118 Pancreatic beta-cell failure in obese mice with human-like CMP-Neu5Ac hydroxylase deficiency. 2011 Jun 1
24 20197272 Extensive enrichment of N-glycolylneuraminic acid in extracellular sialoglycoproteins abundantly synthesized and secreted by human cancer cells. 2010 Jun 2
25 20445087 Colloquium paper: uniquely human evolution of sialic acid genetics and biology. 2010 May 11 2
26 20668298 A human-specific deletion in mouse Cmah increases disease severity in the mdx model of Duchenne muscular dystrophy. 2010 Jul 28 1
27 18777136 Multiple changes in sialic acid biology during human evolution. 2009 Apr 1
28 19666593 The origin of malignant malaria. 2009 Sep 1 2
29 17420276 N-glycolylneuraminic acid deficiency in mice: implications for human biology and evolution. 2007 Jun 1
30 12880951 Reduction of CMP-N-acetylneuraminic acid hydroxylase activity in engineered Chinese hamster ovary cells using an antisense-RNA strategy. 2003 Jul 23 2
31 12192086 Inactivation of CMP-N-acetylneuraminic acid hydroxylase occurred prior to brain expansion during human evolution. 2002 Sep 3 4
32 11589708 Cloning and expression of a membrane-bound CMP-N-acetylneuraminic acid hydroxylase from the starfish Asterias rubens. 2001 Oct 1
33 10052592 The role of CMP-N-acetylneuraminic acid hydroxylase in determining the level of N-glycolylneuraminic acid in porcine tissues. 1998 Sep 1
34 9343941 Functional and biosynthetic aspects of sialic acid diversity. 1997 Feb-Apr 1