| 1 |
35147164 | GLUT4 On the move. | 2022 Feb 11 |
1 |
| 2 |
31759099 | Hepatic insulin resistance induced by mitochondrial oxidative stress can be ameliorated by sphingosine 1-phosphate. | 2020 Feb 5 |
1 |
| 3 |
32998286 | Astaxanthin Inhibits p70 S6 Kinase 1 Activity to Sensitize Insulin Signaling. | 2020 Sep 28 |
1 |
| 4 |
29721854 | Abscisic Acid Supplementation Rescues High Fat Diet-Induced Alterations in Hippocampal Inflammation and IRSs Expression. | 2019 Jan |
2 |
| 5 |
27868170 | Protein kinases: mechanisms and downstream targets in inflammation-mediated obesity and insulin resistance. | 2017 Feb |
1 |
| 6 |
28130417 | Phosphorylation of clustered serine residues in the N-terminus of BPS domain negatively regulates formation of the complex between human Grb14 and insulin receptor. | 2017 Aug 1 |
1 |
| 7 |
27729247 | High fructose-mediated attenuation of insulin receptor signaling does not affect PDGF-induced proliferative signaling in vascular smooth muscle cells. | 2016 Nov 15 |
1 |
| 8 |
25342129 | Dysfunctionally phosphorylated type 1 insulin receptor substrate in neural-derived blood exosomes of preclinical Alzheimer's disease. | 2015 Feb |
1 |
| 9 |
25627174 | Analysis of insulin receptor substrate signaling dynamics on microstructured surfaces. | 2015 Mar |
1 |
| 10 |
24535599 | Phosphorylation of Grb14 BPS domain by GSK-3 correlates with complex forming of Grb14 and insulin receptor. | 2014 Jun |
1 |
| 11 |
25002580 | Deciphering a molecular mechanism of neonatal diabetes mellitus by the chemical synthesis of a protein diastereomer, [D-AlaB8]human proinsulin. | 2014 Aug 22 |
1 |
| 12 |
24101906 | The STAT3-Ser/Hes3 signaling axis: an emerging regulator of endogenous regeneration and cancer growth. | 2013 |
1 |
| 13 |
22609131 | From excess adiposity to insulin resistance: the role of free fatty acids. | 2012 Sep-Oct |
3 |
| 14 |
19887566 | Central insulin signaling is attenuated by long-term insulin exposure via insulin receptor substrate-1 serine phosphorylation, proteasomal degradation, and lysosomal insulin receptor degradation. | 2010 Jan |
2 |
| 15 |
20519504 | Muscleblind-like 1 (Mbnl1) promotes insulin receptor exon 11 inclusion via binding to a downstream evolutionarily conserved intronic enhancer. | 2010 Aug 13 |
1 |
| 16 |
19150387 | Angiotensin II and the development of insulin resistance: implications for diabetes. | 2009 Apr 29 |
1 |
| 17 |
18855718 | The crosstalk between insulin and renin-angiotensin-aldosterone signaling systems and its effect on glucose metabolism and diabetes prevention. | 2008 Oct |
1 |
| 18 |
17347799 | Regulation of insulin receptor function. | 2007 Apr |
1 |
| 19 |
16244361 | Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1. | 2006 Feb |
1 |
| 20 |
16309849 | Induction of heat shock proteins may combat insulin resistance. | 2006 |
1 |
| 21 |
16611834 | Leptin down-regulates insulin action through phosphorylation of serine-318 in insulin receptor substrate 1. | 2006 Jun |
2 |
| 22 |
16839860 | Insulin resistance and cardiovascular risk: New insights from molecular and cellular biology. | 2006 Aug |
1 |
| 23 |
15613682 | Insulin resistance in the skeletal muscle of women with PCOS involves intrinsic and acquired defects in insulin signaling. | 2005 May |
1 |
| 24 |
15713122 | Mechanism of feedback regulation of insulin receptor substrate-1 phosphorylation in primary adipocytes. | 2005 Jun 1 |
1 |
| 25 |
15952059 | PKCdelta and mTOR interact to regulate stress and IGF-I induced IRS-1 Ser312 phosphorylation in breast cancer cells. | 2005 Jun |
1 |
| 26 |
16020478 | Identification of insulin receptor substrate 1 serine/threonine phosphorylation sites using mass spectrometry analysis: regulatory role of serine 1223. | 2005 Oct |
2 |
| 27 |
15075343 | Proreceptor dimerization is required for insulin receptor post-translational processing. | 2004 Jun 11 |
1 |
| 28 |
15494022 | Uncoupling insulin signalling by serine/threonine phosphorylation: a molecular basis for insulin resistance. | 2004 Nov |
1 |
| 29 |
12510059 | Modulation of insulin-stimulated degradation of human insulin receptor substrate-1 by Serine 312 phosphorylation. | 2003 Mar 7 |
1 |
| 30 |
14641043 | Insulin signalling, exercise and cellular integrity. | 2003 Dec |
2 |
| 31 |
11237218 | Insulin resistance in polycystic ovary syndrome: progress and paradoxes. | 2001 |
1 |
| 32 |
11287630 | A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1. | 2001 Apr 10 |
1 |
| 33 |
11381801 | [Intracellular signals involved in glucose control]. | 2001 Mar-Apr |
1 |
| 34 |
11401470 | Identification of Ser(1275) and Ser(1309) as autophosphorylation sites of the human insulin receptor in intact cells. | 2001 Mar 30 |
11 |
| 35 |
11579209 | Phosphorylation of PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptor. | 2001 Oct |
1 |
| 36 |
10694991 | Physiologic and molecular alterations in carbohydrate metabolism during pregnancy and gestational diabetes mellitus. | 2000 Mar |
1 |
| 37 |
10744689 | Phosphorylation of PDE3B by phosphatidylinositol 3-kinase associated with the insulin receptor. | 2000 Apr 7 |
1 |
| 38 |
10804375 | [Polycystic ovary syndrome]. | 2000 May |
1 |
| 39 |
10819237 | Serine residues 994 and 1023/25 are important for insulin receptor kinase inhibition by protein kinase C isoforms beta2 and theta. | 2000 Apr |
2 |
| 40 |
10852715 | A single substitution of the insulin receptor kinase inhibits serine autophosphorylation in vitro: evidence for an interaction between the C-terminus and the activation loop. | 2000 Jun 20 |
3 |
| 41 |
10866039 | Serine residues 1177/78/82 of the insulin receptor are required for substrate phosphorylation but not autophosphorylation. | 2000 Jun |
2 |
| 42 |
10923637 | Involvement of protein kinase C in human skeletal muscle insulin resistance and obesity. | 2000 Aug |
1 |
| 43 |
10338114 | The inhibitory effect of 2-deoxyglucose on insulin receptor autophosphorylation does not depend on known serine phosphorylation sites or other conserved serine residues of the receptor beta-subunit. | 1999 Apr 23 |
2 |
| 44 |
10488146 | JAK1-dependent phosphorylation of insulin receptor substrate-1 (IRS-1) is inhibited by IRS-1 serine phosphorylation. | 1999 Sep 24 |
2 |
| 45 |
10497255 | Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function. | 1999 Oct 1 |
3 |
| 46 |
9922107 | Role of cytochrome P450c17 in polycystic ovary syndrome. | 1998 Oct 25 |
1 |
| 47 |
9000514 | Identification of Ser-1275 and Ser-1309 as autophosphorylation sites of the insulin receptor. | 1997 Jan 2 |
8 |
| 48 |
9243110 | Protein kinase C isoforms beta 1 and beta 2 inhibit the tyrosine kinase activity of the insulin receptor. | 1997 Jul |
1 |
| 49 |
9312143 | 14-3-3 protein binds to insulin receptor substrate-1, one of the binding sites of which is in the phosphotyrosine binding domain. | 1997 Oct 3 |
1 |
| 50 |
9335553 | Protein kinase C modulation of insulin receptor substrate-1 tyrosine phosphorylation requires serine 612. | 1997 Oct 21 |
1 |