Title : Induction of heat shock proteins may combat insulin resistance.

Pub. Date : 2006

PMID : 16309849






1 Functional Relationships(s)
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1 This in turn triggers a kinase cascade which activates both IkappaB kinase-beta (IKK-beta) and c-Jun N-terminal kinase (JNK), each of which can phosphorylate a key serine residue in IRS-1, rendering it a poor substrate for the activated insulin receptor. Serine insulin receptor Homo sapiens