Polyamines

MYC proto-oncogene, bHLH transcription factor ; Homo sapiens







41 Article(s)
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1 35100927 Pharmacological targeting of polyamine and hypusine biosynthesis reduces tumour activity of endometrial cancer. 2022 Jul 4
2 32380424 BCG Vaccinations Upregulate Myc, a Central Switch for Improved Glucose Metabolism in Diabetes. 2020 May 22 1
3 32786875 Allicin, a Potent New Ornithine Decarboxylase Inhibitor in Neuroblastoma Cells. 2020 Aug 28 1
4 31064849 PGC1α Inhibits Polyamine Synthesis to Suppress Prostate Cancer Aggressiveness. 2019 Jul 1 2
5 31164374 MYC-Driven Small-Cell Lung Cancer is Metabolically Distinct and Vulnerable to Arginine Depletion. 2019 Aug 15 1
6 29445227 Novel ubiquitin-independent nucleolar c-Myc degradation pathway mediated by antizyme 2. 2018 Feb 14 1
7 29799508 Myc, Oncogenic Protein Translation, and the Role of Polyamines. 2018 May 25 5
8 30404920 Polyamine synthesis as a target of MYC oncogenes. 2018 Nov 30 3
9 25808495 Competition between RNA-binding proteins CELF1 and HuR modulates MYC translation and intestinal epithelium renewal. 2015 May 15 2
10 26178413 Bag-1 promotes cell survival through c-Myc-mediated ODC upregulation that is not preferred under apoptotic stimuli in MCF-7 cells. 2015 Jul 3
11 26835380 Translational development of difluoromethylornithine (DFMO) for the treatment of neuroblastoma. 2015 Jul 2
12 23144800 Spermine attenuates the action of the DNA intercalator, actinomycin D, on DNA binding and the inhibition of transcription and DNA replication. 2012 1
13 21693166 A stabilizing and denaturing dual-effect for natural polyamines interacting with G-quadruplexes depending on concentration. 2011 Aug 1
14 22195744 The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. 2011 Dec 23 1
15 20103728 Cancer chemoprevention locks onto a new polyamine metabolic target. 2010 Feb 1
16 19147568 Targeting ornithine decarboxylase impairs development of MYCN-amplified neuroblastoma. 2009 Jan 15 1
17 19176757 Polyamines regulate E-cadherin transcription through c-Myc modulating intestinal epithelial barrier function. 2009 Apr 5
18 19324889 Elevated polyamines induce c-MYC overexpression by perturbing quadruplex-WC duplex equilibrium. 2009 Jun 7
19 19789308 Disrupting polyamine homeostasis as a therapeutic strategy for neuroblastoma. 2009 Oct 1 5
20 19812253 Polyamines regulate c-Myc translation through Chk2-dependent HuR phosphorylation. 2009 Dec 6
21 17680562 Altered methionine metabolism and global DNA methylation in liver cancer: relationship with genomic instability and prognosis. 2007 Dec 1 2
22 16439861 Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells. 2006 1
23 16706751 Polyamine-modulated c-Myc expression in normal intestinal epithelial cells regulates p21Cip1 transcription through a proximal promoter region. 2006 Sep 1 7
24 15355849 Polyamine-modulated expression of c-myc plays a critical role in stimulation of normal intestinal epithelial cell proliferation. 2005 Jan 8
25 15768429 Changes in polyamines, c-myc and c-fos gene expression in osteoblast-like cells exposed to pulsed electromagnetic fields. 2005 Apr 2
26 15857080 Depletion of polyamines and increase of transforming growth factor-beta1, c-myc, collagen-type I, matrix metalloproteinase-1, and metalloproteinase-2 mRNA in primary human gingival fibroblasts. 2005 Mar 1
27 16382048 A comprehensive strategy to combat colon cancer targeting the adenomatous polyposis coli tumor suppressor gene. 2005 Nov 1
28 12810952 Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene. 2003 Jun 24 1
29 11443226 Polyamines: new cues in cellular signal transduction. 2001 Jun 1
30 11598794 Down-modulation of c-myc expression by phorbol ester protects CEM T leukaemia cells from starvation-induced apoptosis: role of ornithine decarboxylase and polyamines. 2001 Oct 1
31 10423165 Effects of polyamines, polyamine synthesis inhibitors, and polyamine analogs on casein kinase II using Myc oncoprotein as substrate. 1999 Jul 15 5
32 10535358 The c-myc gene regulates the polyamine pathway in DMSO-induced apoptosis. 1999 Apr-Jun 2
33 10581008 Polyamine depletion up-regulates c-Myc expression, yet induces G(1) arrest and terminal differentiation of F9 teratocarcinoma stem cells. 1999 Nov 5
34 9462700 Inhibition of cell growth in CaCO2 cells by the polyamine analogue N1,N12-bis(ethyl)spermine is preceded by a reduction in MYC oncoprotein levels. 1998 Mar 2
35 8695842 The proto-oncogene c-myc blocks myeloid differentiation independently of its target gene ornithine decarboxylase. 1996 Aug 15 1
36 8929217 Elevated cellular polyamine levels enhance promoter activity in vivo. 1996 Sep 24 1
37 7567474 Suppression of c-myc oncogene expression by a polyamine-complexed triplex forming oligonucleotide in MCF-7 breast cancer cells. 1995 Sep 11 1
38 1378845 Characterization of an endogenous RNA transcript with homology to the antisense strand of the human c-myc gene. 1992 Jul 25 2
39 2511847 Modulation of growth gene expression by selective alteration of polyamines in human colon carcinoma cells. 1989 Nov 30 1
40 3128541 Effect of polyamine depletion on c-myc expression in human colon carcinoma cells. 1988 Apr 25 4
41 3325885 Different regulation of N- and c-myc expression during phorbol ester-induced maturation of human SH-SY5Y neuroblastoma cells. 1987 1