Title : Cancer chemoprevention locks onto a new polyamine metabolic target.

Pub. Date : 2010 Feb

PMID : 20103728






1 Functional Relationships(s)
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1 report new evidence (beginning on p. 140 in this issue of the journal) indicating that spermidine synthase, a fellow enzyme of ornithine decarboxylase in polyamine metabolism, is transactivated in part by the MYC gene and is a potential target for chemoprevention of B-cell lymphomas. Polyamines MYC proto-oncogene, bHLH transcription factor Homo sapiens