Lysine

MYC proto-oncogene, bHLH transcription factor ; Homo sapiens







43 Article(s)
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1 34406978 Circular RNA circRHOT1 contributes to pathogenesis of non-small cell lung cancer by epigenetically enhancing C-MYC expression through recruiting KAT5. 2021 Aug 18 1
2 31948749 WDR5-Myc axis promotes the progression of glioblastoma and neuroblastoma by transcriptional activating CARM1. 2020 Mar 12 1
3 31196146 Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation. 2019 Jun 13 2
4 29511348 Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma. 2018 May 1
5 29653269 MicroRNA-26a is a key regulon that inhibits progression and metastasis of c-Myc/EZH2 double high advanced hepatocellular carcinoma. 2018 Jul 10 1
6 29996811 BET Bromodomain inhibition promotes De-repression of TXNIP and activation of ASK1-MAPK pathway in acute myeloid leukemia. 2018 Jul 11 1
7 30140938 MicroRNA 675 cooperates PKM2 to aggravate progression of human liver cancer stem cells induced from embryonic stem cells. 2018 Oct 2
8 30526305 MYC and RAS are unable to cooperate in overcoming cellular senescence and apoptosis in normal human fibroblasts. 2018 1
9 27358484 c-Myc Modulation and Acetylation Is a Key HDAC Inhibitor Target in Cancer. 2017 May 15 1
10 28209620 The Histone Methyltransferase DOT1L Promotes Neuroblastoma by Regulating Gene Transcription. 2017 May 1 2
11 28653878 Sirtuin 6 plays an oncogenic role and induces cell autophagy in esophageal cancer cells. 2017 Jun 2
12 28806398 Lysine-52 stabilizes the MYC oncoprotein through an SCFFbxw7-independent mechanism. 2017 Dec 7 2
13 27159579 Mapping the chemical chromatin reactivation landscape identifies BRD4-TAF1 cross-talk. 2016 Jul 1
14 27349498 Reversible lysine-specific demethylase 1 antagonist HCI-2509 inhibits growth and decreases c-MYC in castration- and docetaxel-resistant prostate cancer cells. 2016 Dec 1
15 25569455 Acetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC. 2015 Feb 1
16 25895136 c-Myc is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1, SENP7 and RNF4. 2015 1
17 25944903 FBXO32 Targets c-Myc for Proteasomal Degradation and Inhibits c-Myc Activity. 2015 Jun 26 3
18 25977460 A Novel ¹¹¹In-Labeled Anti-Prostate-Specific Membrane Antigen Nanobody for Targeted SPECT/CT Imaging of Prostate Cancer. 2015 Jul 2
19 25995743 Galactosylated poly-L-lysine targeted microbubbles for ultrasound mediated antisense c-myc gene transfection in hepatocellular carcinoma cells. 2015 Apr 25 1
20 26159421 Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression. 2015 Jul 28 2
21 26199140 DOT1L cooperates with the c-Myc-p300 complex to epigenetically derepress CDH1 transcription factors in breast cancer progression. 2015 Jul 22 1
22 23435422 MYC activity is negatively regulated by a C-terminal lysine cluster. 2014 Feb 20 4
23 24435446 Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells. 2014 May 1
24 24608896 SUMOylation of Myc-family proteins. 2014 1
25 23296385 ETA: robust software for determination of cell specific rates from extracellular time courses. 2013 Jun 1
26 22190494 The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop. 2012 Jan 24 3
27 22683437 Protein acetylation mechanisms in the regulation of insulin and insulin-like growth factor 1 signalling. 2012 Oct 15 1
28 22711821 Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation. 2012 Jul 3 1
29 21642861 Histone deacetylase inhibitors sensitize human non-small cell lung cancer cells to ionizing radiation through acetyl p53-mediated c-myc down-regulation. 2011 Aug 1
30 21969221 Epigenetic reprogramming of Myc target genes. 2011 2
31 20418916 LSD1-mediated demethylation of histone H3 lysine 4 triggers Myc-induced transcription. 2010 Jun 24 3
32 20691906 Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation. 2010 Aug 6 3
33 20714214 DNA oxidation drives Myc mediated transcription. 2010 Aug 1 1
34 20940306 Down-regulation of Myc is essential for terminal erythroid maturation. 2010 Dec 17 1
35 18985155 Analysis of Myc-induced histone modifications on target chromatin. 2008 4
36 19047142 N-Myc regulates a widespread euchromatic program in the human genome partially independent of its role as a classical transcription factor. 2008 Dec 1 2
37 17712411 Epidermal stem cells are defined by global histone modifications that are altered by Myc-induced differentiation. 2007 Aug 22 1
38 16126174 Six lysine residues on c-Myc are direct substrates for acetylation by p300. 2005 Oct 14 2
39 16269333 The ubiquitin ligase HectH9 regulates transcriptional activation by Myc and is essential for tumor cell proliferation. 2005 Nov 4 1
40 16287840 Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription. 2005 Dec 3
41 12397066 Determinants of nuclear and cytoplasmic ubiquitin-mediated degradation of MyoD. 2003 Jan 17 1
42 14645543 The c-myc insulator element and matrix attachment regions define the c-myc chromosomal domain. 2003 Dec 2
43 10807912 Degradation of the epstein-barr virus latent membrane protein 1 (LMP1) by the ubiquitin-proteasome pathway. Targeting via ubiquitination of the N-terminal residue. 2000 Aug 4 1