Pub. Date : 2008
PMID : 18985155
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Among other mechanisms, Myc recruits histone acetyl-transferases to target chromatin and locally promotes hyper-acetylation of multiple lysines on histones H3 and H4, although the identity and combination of the modified lysines is unknown. | Lysine | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | Among other mechanisms, Myc recruits histone acetyl-transferases to target chromatin and locally promotes hyper-acetylation of multiple lysines on histones H3 and H4, although the identity and combination of the modified lysines is unknown. | Lysine | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 3 | Here, we used quantitative chromatin immunoprecipitation (qChIP) to profile a total of 24 lysine-acetylation and -methylation marks modulated by Myc at target promoters in a human B-cell line with a regulatable c-myc transgene. | Lysine | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 4 | Myc binding promoted acetylation of multiple lysines, primarily of H3K9, H3K14, H3K18, H4K5 and H4K12, but significantly also of H4K8, H4K91 and H2AK5. | Lysine | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |