Metformin

tumor necrosis factor ; Mus musculus







42 Article(s)
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1 35145895 Aqueous and alcoholic extracts of Artemisia annua L. improved insulin resistance via decreasing TNF-alpha, IL-6 and free fatty acids in high-fat diet/streptozotocin-induced diabetic mice. 2022 Jan-Feb 2
2 35156512 Metformin attenuated sepsis-associated liver injury and inflammatory response in aged mice. 2022 Feb 1
3 35414608 Metformin improves renal injury of MRL/lpr lupus-prone mice via the AMPK/STAT3 pathway. 2022 Apr 1
4 33157041 Combining naringenin and metformin with doxorubicin enhances anticancer activity against triple-negative breast cancer in vitro and in vivo. 2021 Jan 15 1
5 33642112 Possible treatment for UVB-induced skin injury: Anti-inflammatory and cytoprotective role of metformin in UVB-irradiated keratinocytes. 2021 Apr 1
6 33850550 Metformin attenuates diabetic renal injury via the AMPK-autophagy axis. 2021 Jun 1
7 33947424 Metformin ameliorates scleroderma via inhibiting Th17 cells and reducing mTOR-STAT3 signaling in skin fibroblasts. 2021 May 4 1
8 34570348 Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis. 2021 Dec 1
9 31102492 Metformin shows anti-inflammatory effects in murine macrophages through Dicer/microribonucleic acid-34a-5p and microribonucleic acid-125b-5p. 2020 Jan 1
10 31902918 Metformin Suppresses LPS-Induced Inflammatory Responses in Macrophage and Ameliorates Allergic Contact Dermatitis in Mice via Autophagy. 2020 1
11 32189544 Protective effect of metformin against rotenone-induced parkinsonism in mice. 2020 Jun 1
12 30935688 Metformin alleviates inflammatory response in non-alcoholic steatohepatitis by restraining signal transducer and activator of transcription 3-mediated autophagy inhibition in vitro and in vivo. 2019 May 21 1
13 31002870 Metformin ameliorates endotoxemia-induced endothelial pro-inflammatory responses via AMPK-dependent mediation of HDAC5 and KLF2. 2019 Jun 1 2
14 31319131 AMPK as a potential pharmacological target for alleviating LPS-induced acute lung injury partly via NLRC4 inflammasome pathway inhibition. 2019 Oct 1 1
15 28935544 Metformin improves obesity-associated inflammation by altering macrophages polarization. 2018 Feb 5 2
16 29554661 Alkannin Inhibited Hepatic Inflammation in Diabetic Db/Db Mice. 2018 1
17 29859833 Metformin alleviated endotoxemia-induced acute lung injury via restoring AMPK-dependent suppression of mTOR. 2018 Aug 1 1
18 30116349 Metformin exerts anti-inflammatory effects on mouse colon smooth muscle cells in vitro. 2018 Aug 1
19 30242842 Metformin inhibits IgE- and aryl hydrocarbon receptor-mediated mast cell activation in vitro and in vivo. 2018 Dec 1
20 28410530 Metformin attenuated endotoxin-induced acute myocarditis via activating AMPK. 2017 Jun 2
21 28439456 Metformin ameliorates insulitis in STZ-induced diabetic mice. 2017 1
22 28559290 A role for PFKFB3/iPFK2 in metformin suppression of adipocyte inflammatory responses. 2017 Jul 1
23 28827783 Ccdc3: A New P63 Target Involved in Regulation Of Liver Lipid Metabolism. 2017 Aug 21 1
24 28921708 Scopoletin Supplementation Ameliorates Steatosis and Inflammation in Diabetic Mice. 2017 Nov 2
25 27059094 The role of metformin and resveratrol in the prevention of hypoxia-inducible factor 1α accumulation and fibrosis in hypoxic adipose tissue. 2016 Jun 1
26 27252117 The protective potential of metformin against acetaminophen-induced hepatotoxicity in BALB/C mice. 2016 Dec 1
27 28002460 Metformin Improves Ileal Epithelial Barrier Function in Interleukin-10 Deficient Mice. 2016 1
28 24770553 Metformin aggravates immune-mediated liver injury in mice. 2015 Mar 1
29 26265045 AMPK dependent protective effects of metformin on tumor necrosis factor-induced apoptotic liver injury. 2015 Sep 25 3
30 26276089 Effect of metformin and adriamycin on transplantable tumor model. 2015 Oct 1
31 24973221 Metformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction. 2014 Aug 15 4
32 25315906 Metformin attenuates blood-brain barrier disruption in mice following middle cerebral artery occlusion. 2014 Oct 15 1
33 25472042 TallyHO obese female mice experience poor reproductive outcomes and abnormal blastocyst metabolism that is reversed by metformin. 2014 Dec 1
34 25951664 Protective effect of metformin on renal injury of C57BL/6J mouse treated with high fat diet. 2014 Dec 1
35 23557965 Metformin downregulates Th17 cells differentiation and attenuates murine autoimmune arthritis. 2013 May 1
36 24009539 Metformin Down-regulates TNF-α Secretion via Suppression of Scavenger Receptors in Macrophages. 2013 Aug 5
37 24204674 Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. 2013 2
38 22330083 Antidiabetic drug metformin alleviates endotoxin-induced fulminant liver injury in mice. 2012 Apr 2
39 21091653 Metformin inhibits HMGB1 release in LPS-treated RAW 264.7 cells and increases survival rate of endotoxaemic mice. 2011 Apr 1
40 20869956 Ursolic acid ameliorates thymic atrophy and hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice. 2010 Dec 5 1
41 16514202 Role of the N, N'-dimethylbiguanide metformin in the treatment of female prepuberal BALB/c mice hyperandrogenized with dehydroepiandrosterone. 2006 Mar 1
42 14499793 Current biochemical studies of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis suggest a new therapeutic approach. 2003 Sep 3