Title : Protective effect of metformin on renal injury of C57BL/6J mouse treated with high fat diet.

Pub. Date : 2014 Dec

PMID : 25951664






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1 Metformin improved metabolic disorders, upregulated activity of renal AMPK, diminished the expression of renal SREBP-1c, TNF-alpha, NOX4 mRNA, decreased accumulation of renal lipids, and prevened renal injury. Metformin tumor necrosis factor Mus musculus