Tyrosine

epidermal growth factor receptor ; Homo sapiens







1076 Article(s)
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51 31884128 Timing in combination with radiotherapy and patterns of disease progression in non-small cell lung cancer treated with EGFR-TKI. 2020 Feb 2
52 31892990 Inhibition of Tumor Lymphangiogenesis is an Important Part that EGFR-TKIs Play in the Treatment of NSCLC. 2020 2
53 31897229 SFI Enhances Therapeutic Efficiency of Gefitinib: An Insight into Reversal of Resistance to Targeted Therapy in Non-small Cell Lung Cancer Cells. 2020 1
54 31898615 T790M mutations identified by circulating tumor DNA test in lung adenocarcinoma patients who progressed on first-line epidermal growth factor receptor-tyrosine kinase inhibitors. 2020 Jan-Feb 1
55 31901678 Systematic molecular profiling of inhibitor response to the clinical missense mutations of ErbB family kinases in human gastric cancer. 2020 May 2
56 31904278 Detection of EGFR T790M Mutation by Droplet Digital Polymerase Chain Reaction in Lung Carcinoma Cytology Samples. 2020 Jan 6 2
57 31907582 Cyclosporin A activates human hepatocellular carcinoma (HepG2 cells) proliferation: implication of EGFR-mediated ERK1/2 signaling pathway. 2020 May 3
58 31910497 Impact of clinicopathologic features on leptomeningeal metastasis from lung adenocarcinoma and treatment efficacy with epidermal growth factor receptor tyrosine kinase inhibitor. 2020 Feb 2
59 31922964 Successful immune checkpoint inhibition in an EGFR-mutant lung cancer patient refractory to epidermal growth factor receptor tyrosine kinase inhibitor treatment. 2020 Mar 1
60 31926441 Osimertinib treatment for patients with EGFR exon 20 mutation positive non-small cell lung cancer. 2020 Mar 4
61 31931029 Disruption of the EGFR-SQSTM1 interaction by a stapled peptide suppresses lung cancer via activating autophagy and inhibiting EGFR signaling. 2020 Apr 1 1
62 31931137 Afatinib for the Treatment of NSCLC Harboring Uncommon EGFR Mutations: A Database of 693 Cases. 2020 May 1
63 31932478 EHD1 and RUSC2 Control Basal Epidermal Growth Factor Receptor Cell Surface Expression and Recycling. 2020 Mar 16 1
64 31935369 Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway. 2020 Jan 13 3
65 31942192 Efficacy of EGFR-TKIs with or without angiogenesis inhibitors in advanced non-small-cell lung cancer: A systematic review and meta-analysis. 2020 1
66 31943845 Abivertinib in patients with T790M-positive advanced NSCLC and its subsequent treatment with osimertinib. 2020 Mar 2
67 31945708 Clearing of circulating tumour DNA predicts clinical response to first line tyrosine kinase inhibitors in advanced epidermal growth factor receptor mutated non-small cell lung cancer. 2020 Mar 3
68 31945786 Extreme Downregulation of Chromosome Y and Cancer Risk in Men. 2020 Sep 1 1
69 31952541 Musashi2 promotes EGF-induced EMT in pancreatic cancer via ZEB1-ERK/MAPK signaling. 2020 Jan 17 1
70 31956415 Squamous cell transformation as a mechanism of acquired resistance to tyrosine kinase inhibitor in EGFR-mutated lung adenocarcinoma: a report of two cases. 2020 Mar 3
71 31957595 Relationship between epidermal growth factor receptor mutations and skin rash in non-small cell lung cancer patients. 2020 Apr 5
72 31959859 Determination of Somatic Mutations and Tumor Mutation Burden in Plasma by CAPP-Seq during Afatinib Treatment in NSCLC Patients Resistance to Osimertinib. 2020 Jan 20 4
73 31964750 Epidermal Growth Factor Receptor and Transforming Growth Factor β Signaling Pathways Cooperate To Mediate Chlamydia Pathogenesis. 2020 Mar 23 2
74 31969600 Delineation of cell death mechanisms induced by synergistic effects of statins and erlotinib in non-small cell lung cancer cell (NSCLC) lines. 2020 Jan 22 2
75 31977865 Multi-center, randomized, double-blind, placebo-controlled, exploratory study to evaluate the efficacy and safety of HAD-B1 for dose-finding in EGFR positive and locally advanced or metastatic NSCLC subjects who need Afatinib therapy: Study protocol clinical trial (SPIRIT Compliant). 2020 Jan 1
76 31982639 Investigation of efficacy and acquired resistance for EGFR-TKI plus bevacizumab as first-line treatment in patients with EGFR sensitive mutant non-small cell lung cancer in a Real world population. 2020 Mar 1
77 31985315 Serum C-Reactive Protein Level Predicts Clinical Outcomes in Patients With Non-Small Cell Lung Cancer Harboring EGFR Mutations. 2020 Feb 1
78 31988476 Targeting LRIG2 overcomes resistance to EGFR inhibitor in glioblastoma by modulating GAS6/AXL/SRC signaling. 2020 Dec 1
79 31991049 Detection of plasma EGFR mutations for personalized treatment of lung cancer patients without pathologic diagnosis. 2020 Mar 1
80 32000647 Synthesis, Biological and Computational Evaluation of Novel 2,3-dihydro-2-aryl-4-(4- isobutylphenyl)-1,5-benzothiazepine Derivatives as Anticancer and Anti-EGFR Tyrosine Kinase Agents. 2020 4
81 32005236 Correction to: Targeting the epidermal growth factor receptor in non-small cell lung cancer cells: the effect of combining RNA interference with tyrosine kinase inhibitors or cetuximab. 2020 Feb 1 1
82 32011193 A profile on cobas® EGFR Mutation Test v2 as companion diagnostic for first-line treatment of patients with non-small cell lung cancer. 2020 Jun 1
83 32014348 Tyrosine Kinase Inhibitors for the Treatment of EGFR Mutation-Positive Non-Small-Cell Lung Cancer: A Clash of the Generations. 2020 May 4
84 32017710 Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors. 2020 May 1 1
85 32018052 AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells. 2020 Jun 1
86 32023774 [The influence of TP53 mutation on the therapeutic effect of EGFR tyrosine kinase inhibitor and prognosis of EGFR mutant non-small cell lung cancer patients]. 2020 Jan 23 2
87 32024694 A specific amino acid context in EGFR and HER2 phosphorylation sites enables selective binding to the active site of Src homology phosphatase 2 (SHP2). 2020 Mar 13 1
88 32025485 Use of a plasma test for verifying epidermal growth factor receptor gene (EGFR) mutations in fluid samples from non-small cell lung cancer patients. 2020 4
89 32029440 c-Src Phosphorylates and Inhibits the Function of the CIC Tumor Suppressor Protein. 2020 May 1
90 32053675 Clinical significance of EGFR mutation types in lung adenocarcinoma: A multi-centre Korean study. 2020 2
91 32069320 Novel EGFR ectodomain mutations associated with ligand-independent activation and cetuximab resistance in head and neck cancer. 2020 2
92 32069373 Recent advances in targeted small-molecule inhibitor therapy for non-small-cell lung cancer-An update. 2020 Jun 1
93 32070026 Licochalcone D Induces ROS-Dependent Apoptosis in Gefitinib-Sensitive or Resistant Lung Cancer Cells by Targeting EGFR and MET. 2020 Feb 13 2
94 32201537 CD148 Serves as a Prognostic Marker of Gastric Cancer and Hinders Tumor Progression by Dephosphorylating EGFR. 2020 1
95 32439698 AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c-ABL Kinase Pathway in Head and Neck Cancer. 2020 Aug 15 1
96 32439863 PPARδ is a regulator of autophagy by its phosphorylation. 2020 Jun 2
97 32692593 Processing Temporal Growth Factor Patterns by an Epidermal Growth Factor Receptor Network Dynamically Established in Space. 2020 Oct 6 1
98 32860853 Thyroid receptor-interacting protein 13 and EGFR form a feedforward loop promoting glioblastoma growth. 2020 Nov 28 1
99 33000220 Gangliosides and CD82 inhibit the motility of colon cancer by downregulating the phosphorylation of EGFR at different tyrosine sites and signaling pathways. 2020 Nov 1
100 33179922 Phosphorylation-Dependent Conformations of the Disordered Carboxyl-Terminus Domain in the Epidermal Growth Factor Receptor. 2020 Dec 3 1