Title : Synthesis, Biological and Computational Evaluation of Novel 2,3-dihydro-2-aryl-4-(4- isobutylphenyl)-1,5-benzothiazepine Derivatives as Anticancer and Anti-EGFR Tyrosine Kinase Agents.

Pub. Date : 2020

PMID : 32000647






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 These compounds were tested for their inhibitory action against EGFR (Epidermal Growth Factor Receptor) tyrosine kinase taking into account their excellent action against colon and breast cancer cell lines. Tyrosine epidermal growth factor receptor Homo sapiens
2 These compounds were tested for their inhibitory action against EGFR (Epidermal Growth Factor Receptor) tyrosine kinase taking into account their excellent action against colon and breast cancer cell lines. Tyrosine epidermal growth factor receptor Homo sapiens
3 Again the above three compounds showed excellent inhibitory activity with the percentage inhibition of 64.5, 57.3 and 55.8 respectively against EGFR (Epidermal Growth Factor Receptor) tyrosine kinase. Tyrosine epidermal growth factor receptor Homo sapiens
4 Again the above three compounds showed excellent inhibitory activity with the percentage inhibition of 64.5, 57.3 and 55.8 respectively against EGFR (Epidermal Growth Factor Receptor) tyrosine kinase. Tyrosine epidermal growth factor receptor Homo sapiens