| 1 |
34170813 | Synergistic Role of Thymoquinone on Anticancer Activity of 5-Fluorouracil in Triple Negative Breast Cancer Cells. | 2022 |
1 |
| 2 |
34694685 | Cytosolic localization and in vitro assembly of human de novo thymidylate synthesis complex. | 2022 Mar |
2 |
| 3 |
34785778 | Histone N-terminal acetyltransferase NAA40 links one-carbon metabolism to chemoresistance. | 2022 Jan |
4 |
| 4 |
34845374 | Thymidylate synthase O-GlcNAcylation: a molecular mechanism of 5-FU sensitization in colorectal cancer. | 2022 Jan |
3 |
| 5 |
35035999 | Evaluating serum level of thymidylate synthase in post burn keloid patients before and after intralesional injection of 5-fluorouracil. | 2022 Jan-Dec |
6 |
| 6 |
35093082 | FOXM1-induced TYMS upregulation promotes the progression of hepatocellular carcinoma. | 2022 Jan 29 |
2 |
| 7 |
35098910 | Reproductive and developmental toxicities of 5-fluorouracil in model organisms and humans. | 2022 Jan 31 |
1 |
| 8 |
35224365 | Trapping of 5-Fluorodeoxyuridine Monophosphate by Thymidylate Synthase Confers Resistance to 5-Fluorouracil. | 2022 Feb 22 |
16 |
| 9 |
35427566 | Cinobufagin restrains the growth and triggers DNA damage of human hepatocellular carcinoma cells via proteasome-dependent degradation of thymidylate synthase. | 2022 Jun 1 |
2 |
| 10 |
35538714 | Finding alternatives to 5-fluorouracil: application of ensemble-based virtual screening for drug repositioning against human thymidylate synthase. | 2022 May 10 |
1 |
| 11 |
35579160 | An updated review on properties, nanodelivery systems, and analytical methods for the determination of 5-fluorouracil in pharmaceutical and biological samples. | 2022 May 9 |
1 |
| 12 |
33140501 | dUTPase inhibition confers susceptibility to a thymidylate synthase inhibitor in DNA-repair-defective human cancer cells. | 2021 Jan |
2 |
| 13 |
33285053 | Polymorphisms in TYMS for Prediction of Capecitabine-Induced Hand-Foot Syndrome in Chinese Patients with Colorectal Cancer. | 2021 Jul |
2 |
| 14 |
33593942 | AraC-FdUMP[10] Is a Next-Generation Fluoropyrimidine with Potent Antitumor Activity in PDAC and Synergy with PARG Inhibition. | 2021 Apr |
5 |
| 15 |
33613849 | Folinic acid in colorectal cancer: esquire or fellow knight? Real-world results from a mono institutional, retrospective study. | 2021 Feb 2 |
2 |
| 16 |
33636290 | Genomic and immunological features of microsatellite instability in colon cancer. | 2021 May 20 |
2 |
| 17 |
33667525 | TAS-102: A resurrected novel Fluoropyrimidine with expanding role in the treatment of gastrointestinal malignancies. | 2021 Aug |
2 |
| 18 |
33731881 | Mucinous and non-mucinous colorectal cancers show differential expression of chemotherapy metabolism and resistance genes. | 2021 Aug |
1 |
| 19 |
33805673 | Molecular Mechanisms and Tumor Biological Aspects of 5-Fluorouracil Resistance in HCT116 Human Colorectal Cancer Cells. | 2021 Mar 13 |
4 |
| 20 |
33806077 | Coptidis Rhizoma Extract Reverses 5-Fluorouracil Resistance in HCT116 Human Colorectal Cancer Cells via Modulation of Thymidylate Synthase. | 2021 Mar 25 |
6 |
| 21 |
34035223 | Retraction Note to: FOXM1 modulates 5-fluorouracil sensitivity in cholangiocarcinoma through thymidylate synthase (TYMS): implications of FOXM1-TYMS axis uncoupling in 5-FU resistance. | 2021 May 25 |
3 |
| 22 |
34100299 | Gender-dependent association of TYMS-TSER polymorphism with 5-fluorouracil or capecitabine-based chemotherapy toxicity. | 2021 Jul |
6 |
| 23 |
34205990 | Ultrasound-Triggered Release of 5-Fluorouracil from Soy Lecithin Echogenic Liposomes. | 2021 Jun 1 |
1 |
| 24 |
34276810 | Alternative chemoradiotherapy in anal carcinoma patients with mutations in thymidylate synthase and dihydropyrimidine dehydrogenase genes. | 2021 |
3 |
| 25 |
34440086 | Predicting Agents That Can Overcome 5-FU Resistance in Colorectal Cancers via Pharmacogenomic Analysis. | 2021 Jul 24 |
1 |
| 26 |
34528330 | Expression of astrocyte-elevated gene-1 indicates prognostic value of fluoropyrimidine-based adjuvant chemotherapy in resectable stage III colorectal cancer. | 2021 Nov |
2 |
| 27 |
34562873 | Apigenin enhances apoptosis induction by 5-fluorouracil through regulation of thymidylate synthase in colorectal cancer cells. | 2021 Nov |
9 |
| 28 |
34571731 | Recent Updates on Mechanisms of Resistance to 5-Fluorouracil and Reversal Strategies in Colon Cancer Treatment. | 2021 Aug 31 |
1 |
| 29 |
34640443 | Cardiotoxicity of Fluoropyrimidines: Epidemiology, Mechanisms, Diagnosis, and Management. | 2021 Sep 27 |
1 |
| 30 |
34688691 | FOXM1 inhibitor, Siomycin A, synergizes and restores 5-FU cytotoxicity in human cholangiocarcinoma cell lines via targeting thymidylate synthase. | 2021 Dec 1 |
7 |
| 31 |
34901834 | A narrative review of genetic factors affecting fluoropyrimidine toxicity. | 2021 Dec |
1 |
| 32 |
31754833 | High gamma-glutamyl hydrolase and low folylpolyglutamate synthetase expression as prognostic biomarkers in patients with locally advanced gastric cancer who were administrated postoperative adjuvant chemotherapy with S-1. | 2020 Jan |
2 |
| 33 |
32073706 | MicroRNA-375-3p enhances chemosensitivity to 5-fluorouracil by targeting thymidylate synthase in colorectal cancer. | 2020 May |
3 |
| 34 |
32118594 | Prognostic and Predictive Role of Excision Repair Cross-complementation Group 1 and Thymidylate Synthase in Colorectal Carcinoma Patients Received FOLFOX Chemotherapy: An Immunohistochemical Study. | 2020 Nov/Dec |
1 |
| 35 |
32348733 | On a New Proposed Mechanism of 5-Fluorouracil-Mediated Cytotoxicity. | 2020 May |
2 |
| 36 |
32382808 | Phase I pharmacological study of continuous chronomodulated capecitabine treatment. | 2020 May 7 |
2 |
| 37 |
32474153 | Cysteinyl leukotriene receptor 1 promotes 5-fluorouracil resistance and resistance-derived stemness in colon cancer cells. | 2020 Sep 28 |
1 |
| 38 |
32585842 | A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells. | 2020 Jun 23 |
2 |
| 39 |
32675286 | Inhibition of the ATR kinase enhances 5-FU sensitivity independently of nonhomologous end-joining and homologous recombination repair pathways. | 2020 Sep 11 |
1 |
| 40 |
32689938 | Transcriptomic analysis on the effects of melatonin in gastrointestinal carcinomas. | 2020 Jul 20 |
1 |
| 41 |
32708710 | Detection of a G-Quadruplex as a Regulatory Element in Thymidylate synthase for Gene Silencing Using Polypurine Reverse Hoogsteen Hairpins. | 2020 Jul 16 |
2 |
| 42 |
32751071 | Chemistry of Fluorinated Pyrimidines in the Era of Personalized Medicine. | 2020 Jul 29 |
6 |
| 43 |
32838518 | Multiaction Platinum(IV) Prodrug Containing Thymidylate Synthase Inhibitor and Metabolic Modifier against Triple-Negative Breast Cancer. | 2020 Sep 8 |
1 |
| 44 |
32907836 | 5-Fluorouracil Enhances the Antitumor Activity of the Glutaminase Inhibitor CB-839 against PIK3CA-Mutant Colorectal Cancers. | 2020 Nov 1 |
1 |
| 45 |
33005290 | Molecular determinants of response to 5-fluorouracil-based chemotherapy in colorectal cancer: The undisputable role of micro-ribonucleic acids. | 2020 Sep 15 |
1 |
| 46 |
33024525 | Relationship between the Expression of the Thymidylate Synthase and the Prognosis of Gastric Cancer Patients Treated with Combinational Chemotherapy Regimen Including Fluorouracil, Docetaxel and Cisplatin. | 2020 Jul 1 |
2 |
| 47 |
33033767 | In silico design and evaluation of novel 5-fluorouracil analogues as potential anticancer agents. | 2020 Sep |
1 |
| 48 |
33051247 | Pharmacokinetic and Pharmacodynamic Factors Contribute to Synergism between Let-7c-5p and 5-Fluorouracil in Inhibiting Hepatocellular Carcinoma Cell Viability. | 2020 Dec |
2 |
| 49 |
33086767 | A Novel Nomenclature for Repeat Motifs in the Thymidylate Synthase Enhancer Region and Its Relevance for Pharmacogenetic Studies. | 2020 Oct 19 |
4 |
| 50 |
33117504 | Correlation between polymorphism of TYMS gene and toxicity response to treatment with 5-fluoruracil and capecitabine. | 2020 Sep 30 |
1 |