Title : TAS-102: A resurrected novel Fluoropyrimidine with expanding role in the treatment of gastrointestinal malignancies.

Pub. Date : 2021 Aug

PMID : 33667525






2 Functional Relationships(s)
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1 In contrast, 5-fluorouracil (5-FU) interferes with DNA biosynthesis by inhibiting thymidylate synthase(TS), which partly explains the absence of cross-resistance between TAS-102 and 5-FU. Fluorouracil thymidylate synthetase Homo sapiens
2 In contrast, 5-fluorouracil (5-FU) interferes with DNA biosynthesis by inhibiting thymidylate synthase(TS), which partly explains the absence of cross-resistance between TAS-102 and 5-FU. Fluorouracil thymidylate synthetase Homo sapiens