Sirolimus

interleukin 6 ; Mus musculus







29 Article(s)
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1 32567086 HSP90 inhibitors strengthen extracellular ATP-stimulated synthesis of interleukin-6 in osteoblasts: Amplification of p38 MAP kinase. 2021 Jan 1
2 33116044 Intestinal Dysbiosis Correlates With Sirolimus-induced Metabolic Disorders in Mice. 2021 May 1 1
3 34065421 Rapamycin Alternatively Modifies Mitochondrial Dynamics in Dendritic Cells to Reduce Kidney Ischemic Reperfusion Injury. 2021 May 20 1
4 35058778 Magnesium Isoglycyrrhizinate Ameliorates Concanavalin A-Induced Liver Injury by Inhibiting Autophagy. 2021 1
5 33350241 [Autophagic activity of piperine on small intestine in dementia model mice with Parkinson's disease]. 2020 Nov 2
6 31231866 Neural sphingosine 1-phosphate accumulation activates microglia and links impaired autophagy and inflammation. 2019 Oct 4
7 31803045 Melatonin and Rapamycin Attenuate Isoflurane-Induced Cognitive Impairment Through Inhibition of Neuroinflammation by Suppressing the mTOR Signaling in the Hippocampus of Aged Mice. 2019 1
8 29673286 Inhibition of autophagy with 3-methyladenine is protective in a lethal model of murine endotoxemia and polymicrobial sepsis. 2018 May 1
9 27692982 mTORC1 inhibition with rapamycin exacerbates adipose tissue inflammation in obese mice and dissociates macrophage phenotype from function. 2017 Feb 1
10 28182002 Rapamycin upregulates glutamate transporter and IL-6 expression in astrocytes in a mouse model of Parkinson's disease. 2017 Feb 9 4
11 28333137 The mTOR signal regulates myeloid-derived suppressor cells differentiation and immunosuppressive function in acute kidney injury. 2017 Mar 23 1
12 26053964 Rapamycin inhibition of eosinophil differentiation attenuates allergic airway inflammation in mice. 2015 Oct 1
13 26147250 MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation. 2015 Aug 1
14 24742865 Antiangiogenic therapy using sunitinib combined with rapamycin retards tumor growth but promotes metastasis. 2014 Apr 2
15 23426399 Induction of cytokines and growth factors by rapamycin in the microenvironment of brain metastases of lung cancer. 2013 Mar 1
16 23480027 Sirolimus ameliorates inflammatory responses by switching the regulatory T/T helper type 17 profile in murine colitis. 2013 Aug 1
17 23716625 Chemical injury-induced corneal opacity and neovascularization reduced by rapamycin via TGF-β1/ERK pathways regulation. 2013 Jul 2 2
18 23105977 Intranasal rapamycin rescues mice from staphylococcal enterotoxin B-induced shock. 2012 Sep 1
19 22040565 Inactivation of mammalian target of rapamycin (mTOR) by rapamycin in a murine model of lipopolysaccharide-induced acute lung injury. 2011 Oct 1
20 19879324 p70 S6 kinase limits tumor necrosis factor-alpha-induced interleukin-6 synthesis in osteoblast-like cells. 2010 Feb 5 1
21 20086156 Rapamycin protects mice from staphylococcal enterotoxin B-induced toxic shock and blocks cytokine release in vitro and in vivo. 2010 Mar 2
22 20506342 Treatment with rapamycin prevents fibrosis in tight-skin and bleomycin-induced mouse models of systemic sclerosis. 2010 Aug 1
23 19220291 Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor. 2009 Mar 1
24 20005342 Effects of delayed rapamycin treatment on renal fibrosis and inflammation in experimental ischemia reperfusion injury. 2009 Dec 1
25 18372239 P70 S6 kinase negatively regulates fibroblast growth factor 2-stimulated interleukin-6 synthesis in osteoblasts: function at a point downstream from protein kinase C. 2008 Apr 1
26 18480312 Differential effects of rapamycin in anti-GBM glomerulonephritis. 2008 Aug 1
27 17379004 Limitation by p70 S6 kinase of platelet-derived growth factor-BB-induced interleukin 6 synthesis in osteoblast-like MC3T3-E1 cells. 2007 Apr 1
28 7520778 The immunosuppressant rapamycin blocks in vitro responses to hematopoietic cytokines and inhibits recovering but not steady-state hematopoiesis in vivo. 1994 Sep 1 2
29 1987692 Synergistic interactions of cyclosporine and rapamycin to inhibit immune performances of normal human peripheral blood lymphocytes in vitro. 1991 Jan 1