Title : Inactivation of mammalian target of rapamycin (mTOR) by rapamycin in a murine model of lipopolysaccharide-induced acute lung injury.

Pub. Date : 2011 Oct

PMID : 22040565






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Rapa reduced the levels of TNF-alpha (LPS vs. LPS + Rapa, (1672.74 +- 193.73) vs. (539.17 +- 140.48) pg/ml, respectively; P < 0.01) and IL-6 (LPS vs. LPS + Rapa: (7790.88 +- 1170.54) vs. (1968.57 +- 474.62) pg/ml, respectively; P < 0.01) in the BAL fluid. Sirolimus interleukin 6 Mus musculus