Title : Effects of delayed rapamycin treatment on renal fibrosis and inflammation in experimental ischemia reperfusion injury.

Pub. Date : 2009 Dec

PMID : 20005342






1 Functional Relationships(s)
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1 Rapamycin treatment showed minimal effects on postischemic kidney fibrosis with variable effects on various cytokine/chemokine protein expressions, namely, decreasing interleukin (IL)-1alpha, IL-6, tumor necrosis factor (TNF)-alpha, and regulated on activation normal T cell expressed and secreted (RANTES) while increasing IL-4, keratinocyte-derived chemokine (KC), macrophage inflammatory protein (MIP-1alpha), and IL-10 in the ischemic kidney. Sirolimus interleukin 6 Mus musculus