Isoflavones

AKT serine/threonine kinase 1 ; Homo sapiens







13 Article(s)
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1 34249417 A preclinical report of a cobimetinib-inspired novel anticancer small-molecule scaffold of isoflavones, NSC777213, for targeting PI3K/AKT/mTOR/MEK in multiple cancers. 2021 1
2 34873494 Erratum: A preclinical report of a cobimetinib-inspired novel anticancer small-molecule scaffold of isoflavones, NSC777213, for targeting PI3K/AKT/mTOR/MEK in multiple cancers. 2021 1
3 29496164 Dietary isoflavone daidzein synergizes centchroman action via induction of apoptosis and inhibition of PI3K/Akt pathway in MCF-7/MDA MB-231 human breast cancer cells. 2018 Feb 1 1
4 29761845 The O-methylated isoflavone, formononetin, inhibits human ovarian cancer cell proliferation by sub G0/G1 cell phase arrest through PI3K/AKT and ERK1/2 inactivation. 2018 Sep 1
5 23272911 Deregulation of PI3K/Akt/mTOR signaling pathways by isoflavones and its implication in cancer treatment. 2013 Sep 2
6 22412975 Targeting bone remodeling by isoflavone and 3,3'-diindolylmethane in the context of prostate cancer bone metastasis. 2012 1
7 20107864 A phase II study of isoflavones, erlotinib, and gemcitabine in advanced pancreatic cancer. 2011 Aug 1
8 21161820 Estrogen receptor-β mediates the inhibition of DLD-1 human colon adenocarcinoma cells by soy isoflavones. 2011 1
9 22200028 Induction of cancer cell death by isoflavone: the role of multiple signaling pathways. 2011 Oct 1
10 20177775 Effect of combination treatment of rapamycin and isoflavones on mTOR pathway in human glioblastoma (U87) cells. 2010 Jul 2
11 19472400 NV-128, a novel isoflavone derivative, induces caspase-independent cell death through the Akt/mammalian target of rapamycin pathway. 2009 Jul 15 1
12 18687691 Regulation of Akt/FOXO3a/GSK-3beta/AR signaling network by isoflavone in prostate cancer cells. 2008 Oct 10 3
13 16840783 The isoflavone Equol mediates rapid vascular relaxation: Ca2+-independent activation of endothelial nitric-oxide synthase/Hsp90 involving ERK1/2 and Akt phosphorylation in human endothelial cells. 2006 Sep 15 2