Pub. Date : 2010 Jul
PMID : 20177775
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study we investigated the effect of combination treatment of rapamycin with isoflavones such as genistein and biochanin A on mTOR pathway and activation of Akt and eIF4E in human glioblastoma (U87) cells. | Isoflavones | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Our results show that combination treatment of rapamycin with isoflavones, especially biochanin A at 50 muM, decreased the phosphorylation of Akt and eIF4E proteins and rendered U87 cells more sensitive to rapamycin treatment when compared to cells treated with rapamycin alone. | Isoflavones | AKT serine/threonine kinase 1 | Homo sapiens |