| 1 |
34836271 | Genistein Regulates Lipid Metabolism via Estrogen Receptor β and Its Downstream Signal Akt/mTOR in HepG2 Cells. | 2021 Nov 10 |
1 |
| 2 |
31795012 | Genistein protects against amyloid-beta-induced toxicity in SH-SY5Y cells by regulation of Akt and Tau phosphorylation. | 2020 Apr |
3 |
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31903460 | Multifunctional hybrid nanoconstructs facilitate intracellular localization of doxorubicin and genistein to enhance apoptotic and anti-angiogenic efficacy in breast adenocarcinoma. | 2020 Mar 7 |
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| 4 |
32078221 | Anti-invasive effect and pharmacological mechanism of genistein against colorectal cancer. | 2020 Jul |
1 |
| 5 |
32276266 | Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways. | 2020 Apr 10 |
4 |
| 6 |
33164393 | [Molecular mechanism of Puerariae Lobatae Radix in treatment of hepatocellular carcinoma based on network pharmacology]. | 2020 Sep |
2 |
| 7 |
31438633 | Induction of G2/M Cell Cycle Arrest and Apoptosis by Genistein in Human Bladder Cancer T24 Cells through Inhibition of the ROS-Dependent PI3k/Akt Signal Transduction Pathway. | 2019 Aug 21 |
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31611933 | Inhibitory effects of genistein in combination with gefitinib on the hepatocellular carcinoma Hep3B cell line. | 2019 Nov |
2 |
| 9 |
31638174 | Genistein improves viability, proliferation and mitochondrial function of cardiomyoblasts cultured in physiologic and peroxidative conditions. | 2019 Dec |
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| 10 |
31950019 | Genistein Inhibits Proliferation of BRCA1 Mutated Breast Cancer Cells: The GPR30-Akt Axis as a Potential Target. | 2019 Dec |
3 |
| 11 |
29344275 | Genistein Promotes Proliferation of Human Cervical Cancer Cells Through Estrogen Receptor-Mediated PI3K/Akt-NF-κB Pathway. | 2018 |
2 |
| 12 |
29636868 | Novasoy and genistein inhibit endometrial cancer cell proliferation through disruption of the AKT/mTOR and MAPK signaling pathways. | 2018 |
2 |
| 13 |
29693152 | Genistein reduces the activation of AKT and EGFR, and the production of IL6 in cholangiocarcinoma cells involving estrogen and estrogen receptors. | 2018 Jul |
1 |
| 14 |
29743815 | Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer. | 2018 |
3 |
| 15 |
28259980 | Genistein decreases A549 cell viability via inhibition of the PI3K/AKT/HIF‑1α/VEGF and NF‑κB/COX‑2 signaling pathways. | 2017 Apr |
2 |
| 16 |
28627607 | Inactivation of AKT, ERK and NF-κB by genistein derivative, 7-difluoromethoxyl-5,4'-di-n-octylygenistein, reduces ovarian carcinoma oncogenicity. | 2017 Aug |
1 |
| 17 |
28698543 | Genistein Protects Genioglossus Myoblast Against Hypoxia-induced Injury through PI3K-Akt and ERK MAPK Pathways. | 2017 Jul 11 |
3 |
| 18 |
25880142 | Genistein induces activation of the mitochondrial apoptosis pathway by inhibiting phosphorylation of Akt in colorectal cancer cells. | 2016 |
4 |
| 19 |
27121018 | Trichostatin A potentiates genistein-induced apoptosis and reverses EMT in HEp2 cells. | 2016 Jun |
2 |
| 20 |
25362531 | Membrane steroid receptor-mediated action of soy isoflavones: tip of the iceberg. | 2015 Feb |
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| 21 |
25613518 | Calycosin and genistein induce apoptosis by inactivation of HOTAIR/p-Akt signaling pathway in human breast cancer MCF-7 cells. | 2015 |
2 |
| 22 |
25675448 | Genistein induces apoptosis by the inactivation of the IGF-1R/p-Akt signaling pathway in MCF-7 human breast cancer cells. | 2015 Mar |
3 |
| 23 |
25871428 | Genistein inhibits human colorectal cancer growth and suppresses miR-95, Akt and SGK1. | 2015 |
4 |
| 24 |
25915610 | Genistein: A Boon for Mitigating Ischemic Stroke. | 2015 |
1 |
| 25 |
24669186 | Genistein suppresses tumor necrosis factor α-induced inflammation via modulating reactive oxygen species/Akt/nuclear factor κB and adenosine monophosphate-activated protein kinase signal pathways in human synoviocyte MH7A cells. | 2014 |
2 |
| 26 |
24933099 | Insulin-like modulation of Akt/FoxO signaling by copper ions is independent of insulin receptor. | 2014 Sep 15 |
1 |
| 27 |
25260311 | Integration of genomic information in the clinical management of HCC. | 2014 Oct |
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| 28 |
23761822 | Genistein inhibits estradiol- and environmental endocrine disruptor-induced growth effects on neuroblastoma cells in vitro. | 2013 May |
3 |
| 29 |
24053672 | Genistein induces G2/M arrest in gastric cancer cells by increasing the tumor suppressor PTEN expression. | 2013 |
1 |
| 30 |
22098108 | Inhibition of IGF-1 signaling by genistein: modulation of E-cadherin expression and downregulation of β-catenin signaling in hormone refractory PC-3 prostate cancer cells. | 2012 |
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| 31 |
22263786 | Genistein potentiates the anti-cancer effects of gemcitabine in human osteosarcoma via the downregulation of Akt and nuclear factor-κB pathway. | 2012 Jun |
2 |
| 32 |
22504913 | Environmental estrogens differentially engage the histone methyltransferase EZH2 to increase risk of uterine tumorigenesis. | 2012 Apr |
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| 33 |
22801313 | [The action of PI3K/AKT during genistein promoting the activity of eNOS]. | 2012 Apr |
4 |
| 34 |
23056046 | Sensitization of Cervical Cancer Cells to Cisplatin by Genistein: The Role of NFκB and Akt/mTOR Signaling Pathways. | 2012 |
2 |
| 35 |
20107864 | A phase II study of isoflavones, erlotinib, and gemcitabine in advanced pancreatic cancer. | 2011 Aug |
1 |
| 36 |
20658545 | Down-regulation of Notch-1 is associated with Akt and FoxM1 in inducing cell growth inhibition and apoptosis in prostate cancer cells. | 2011 Jan |
1 |
| 37 |
21078540 | Genistein potentiates the effect of arsenic trioxide against human hepatocellular carcinoma: role of Akt and nuclear factor-κB. | 2011 Feb 1 |
3 |
| 38 |
21639915 | Genistein inhibits proliferation of colon cancer cells by attenuating a negative effect of epidermal growth factor on tumor suppressor FOXO3 activity. | 2011 Jun 3 |
1 |
| 39 |
19932626 | Down-regulation of Bcl-2 and Akt induced by combination of photoactivated hypericin and genistein in human breast cancer cells. | 2010 Jan 21 |
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| 40 |
20038829 | Enhanced anticancer effect of gemcitabine by genistein in osteosarcoma: the role of Akt and nuclear factor-kappaB. | 2010 Mar |
2 |
| 41 |
20049867 | Global phosphoproteomic effects of natural tyrosine kinase inhibitor, genistein, on signaling pathways. | 2010 Mar |
1 |
| 42 |
20067990 | Genistein induces enhanced growth promotion in ER-positive/erbB-2-overexpressing breast cancers by ER-erbB-2 cross talk and p27/kip1 downregulation. | 2010 Apr |
1 |
| 43 |
20177775 | Effect of combination treatment of rapamycin and isoflavones on mTOR pathway in human glioblastoma (U87) cells. | 2010 Jul |
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| 44 |
20397699 | Effect of genistein and daidzein on the proliferation and differentiation of human preadipocyte cell line. | 2010 May 12 |
2 |
| 45 |
20730632 | Inhibition of cancer cell invasion and metastasis by genistein. | 2010 Sep |
1 |
| 46 |
20798528 | Genistein suppression of TNF-alpha-induced fractalkine expression in endothelial cells. | 2010 |
1 |
| 47 |
20926919 | Genistein activates endothelial nitric oxide synthase in broiler pulmonary arterial endothelial cells by an Akt-dependent mechanism. | 2010 Nov 30 |
3 |
| 48 |
19107739 | Genistein down-regulates the constitutive activation of nuclear factor-kappaB in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. | 2009 Jun |
2 |
| 49 |
19212674 | Synergistic cell growth inhibition by the combination of amrubicin and Akt-suppressing tyrosine kinase inhibitors in small cell lung cancer cells: implication of c-Src and its inhibitor. | 2009 Mar |
1 |
| 50 |
19373614 | Effects of selenite and genistein on G2/M cell cycle arrest and apoptosis in human prostate cancer cells. | 2009 |
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