Pub. Date : 2001 Aug 24
PMID : 11445557
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of Akt/PKB activation by tyrosine phosphorylation. | Tyrosine | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Regulation of Akt/PKB activation by tyrosine phosphorylation. | Tyrosine | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Here, we present evidence that tyrosine phosphorylation is required for Akt activation. | Tyrosine | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | Epidermal growth factor treatment induces tyrosine phosphorylation of Akt in COS1 and PC3M cells, which is abrogated by PP2, a selective inhibitor for Src family tyrosine kinases. | Tyrosine | AKT serine/threonine kinase 1 | Homo sapiens |
| 5 | Furthermore, we have identified two tyrosine residues near the activation loop of Akt that are important for its activation. | Tyrosine | AKT serine/threonine kinase 1 | Homo sapiens |
| 6 | Our data suggest that, in addition to phosphorylation of Thr(308) and Ser(473), tyrosine phosphorylation of Akt may be essential for its biological function. | Tyrosine | AKT serine/threonine kinase 1 | Homo sapiens |