Pub. Date : 2022 Aug 25
PMID : 35525345
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arsenic exposure elevated ROS promotes energy metabolic reprogramming with enhanced AKT-dependent HK2 expression. | ros | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Further studies showed accumulated ROS determined the metabolic reprogramming via activating AKT and then increasing HK2 expression. | ros | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Taken together, our results indicated that ROS induced by low-dose arsenic exposure determined energy metabolic reprogramming and acted a critical regulator for AKT-dependent HK2 expression and aerobic glycolysis. | ros | AKT serine/threonine kinase 1 | Homo sapiens |