diaziquone

NAD(P)H quinone dehydrogenase 1 ; Homo sapiens







13 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 12859987 Cytotoxicity of RH1 and related aziridinylbenzoquinones: involvement of activation by NAD(P)H:quinone oxidoreductase (NQO1) and oxidative stress. 2003 Aug 1 3
2 14666706 Activity profile of the novel aziridinylbenzoquinones MeDZQ and RH1 in human tumour xenografts. 2003 Sep-Oct 1
3 11999125 Development of a lyophilised RH1 formulation: a novel DT diaphorase activated alkylating agent. 2002 Apr 1
4 11606119 Aziridinyl quinone antitumor agents based on indoles and cyclopent[b]indoles: structure-activity relationships for cytotoxicity and antitumor activity. 2001 Oct 25 1
5 9548807 Induction of p53 by the concerted actions of aziridine and quinone moieties of diaziquone. 1998 Apr 1
6 9865924 A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent. 1998 Dec 2
7 7836380 DT-diaphorase. Redox potential, steady-state, and rapid reaction studies. 1995 Jan 20 1
8 1301071 Reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells. II. Enhancement of the alkylating activity of AZQ by NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase). 1992 Oct 20 3
9 1372518 Alteration in DNA cross-linking and sequence selectivity of a series of aziridinylbenzoquinones after enzymatic reduction by DT-diaphorase. 1992 Mar 24 1
10 1406604 Relationship between DT-diaphorase-mediated metabolism of a series of aziridinylbenzoquinones and DNA damage and cytotoxicity. 1992 Sep 1
11 1654286 The reductive metabolism of diaziquone (AZQ) in the S9 fraction of MCF-7 cells: free radical formation and NAD(P)H: quinone-acceptor oxidoreductase (DT-diaphorase) activity. 1991 2
12 1718826 A note on the inhibition of DT-diaphorase by dicoumarol. 1991 1
13 2121335 Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells. 1990 Nov 15 9