Title : NQO1 Deficiency Leads Enhanced Autophagy in Cisplatin-Induced Acute Kidney Injury Through the AMPK/TSC2/mTOR Signaling Pathway.

Pub. Date : 2016 May 20

PMID : 26935540






1 Functional Relationships(s)
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1 RESULTS: In vitro, NQO1 and autophagy-associated proteins were induced after cisplatin treatment and the autophagosomes markedly increased in the cisplatin-treated NQO1-knockdown ACHN cells together with increased ROS production. Reactive Oxygen Species NAD(P)H quinone dehydrogenase 1 Homo sapiens