Pub. Date : 1993 May
PMID : 8474436
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Squalene synthetase (farnesyl diphosphate:farnesyl diphosphate farnesyltransferase; EC 2.5.1.21) is thought to represent a major control point of isoprene and sterol biosynthesis in eukaryotes. | Sterols | farnesyl-diphosphate farnesyltransferase 1 | Homo sapiens |
| 2 | Inhibition of sterol synthesis in S. cerevisiae and S. pombe cells or in cultured human fibroblasts by treatment with the 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor lovastatin resulted in elevated levels of squalene synthetase mRNA in all three cell types. | Sterols | farnesyl-diphosphate farnesyltransferase 1 | Homo sapiens |