Losartan

angiotensin II receptor, type 1a ; Rattus norvegicus







504 Article(s)
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1 32719462 Maternal high-fat diet increases vascular contractility in adult offspring in a sex-dependent manner. 2021 Jan 2
2 33771655 trans-Anethole attenuated renal injury and reduced expressions of angiotensin II receptor (AT1R) and TGF-β in streptozotocin-induced diabetic rats. 2021 Jun 2
3 33798796 Evaluation of the high affinity [18F]fluoropyridine-candesartan in rats for PET imaging of renal AT1 receptors. 2021 May-Jun 3
4 33991491 Preliminary study of ovariectomy and chronic losartan-induced alterations in brain AT1 receptors. 2021 Sep 1 4
5 34042283 Losartan improved hippocampal long-term potentiation impairment induced by repeated LPS injection in rats. 2021 May 1
6 34252405 Angiotensin II type 1 receptor blockade attenuates posttraumatic stress disorder-related chronic pain by inhibiting glial activation in the spinal cord. 2021 Sep 15 1
7 34502113 Effect of Angiotensin II on Chondrocyte Degeneration and Protection via Differential Usage of Angiotensin II Receptors. 2021 Aug 25 1
8 34779863 Paternal long-term PM2.5 exposure causes hypertension via increased renal AT1R expression and function in male offspring. 2021 Nov 26 2
9 31583926 Acute restraint stress increases blood pressure and oxidative stress in the cardiorenal system of rats: a role for AT1 receptors. 2020 May 1
10 31630435 Chronic treatment with apelin, losartan and their combination reduces myocardial infarct size and improves cardiac mechanical function. 2020 Mar 2
11 31637567 The Angiotensin Type 1 Receptor Antagonist Losartan Prevents Ovariectomy-Induced Cognitive Dysfunction and Anxiety-Like Behavior in Long Evans Rats. 2020 Apr 1
12 32169442 Similarity and dissimilarity between angiotensin A and angiotensin II in cardiovascular functions in a rat model. 2020 Mar 10 2
13 32240022 Central AT1 receptor signaling by circulating angiotensin II is permissive to acute intermittent hypoxia-induced sympathetic neuroplasticity. 2020 May 1 1
14 32791093 Increased endothelial nitric oxide production after low level lead exposure in rats involves activation of angiotensin II receptors and PI3K/Akt pathway. 2020 Oct 1
15 32915316 Interleukin-1β in hypothalamic paraventricular nucleus mediates excitatory renal reflex. 2020 Nov 1
16 29429366 The enhancement of serotonin-induced contraction of rat femoral artery is mediated by angiotensin II release from intact endothelium. 2019 Feb 1
17 30412649 A novel role of angiotensin II in epidermal cell lineage determination: Angiotensin II promotes the differentiation of mesenchymal stem cells into keratinocytes through the p38 MAPK, JNK and JAK2 signalling pathways. 2019 Jan 1
18 30624974 AT1 receptors in the subfornical organ modulate arterial pressure and the baroreflex in two-kidney, one-clip hypertensive rats. 2019 Feb 1 1
19 30731141 Losartan treatment attenuates the development of neuropathic thermal hyperalgesia induced by peripheral nerve injury in rats. 2019 Mar 1 1
20 30945263 Bradykinin increases BP in endotoxemic rat: functional and biochemical evidence of angiotensin II AT1 /bradykinin B2 receptor heterodimerization. 2019 Jul 2
21 31054884 Angiotensin II triggers autophagy and apoptosis in PC12 cell line: An in vitro Alzheimer's disease model. 2019 Sep 1 1
22 31241170 Endogenous AT1 receptor-protein kinase C activity in the hypothalamus augments glutamatergic input and sympathetic outflow in hypertension. 2019 Aug 1
23 31468138 Fast relaxation and desensitization of angiotensin II contraction in the pulmonary artery via AT1R and Akt-mediated phosphorylation of muscular eNOS. 2019 Oct 1
24 31606204 Spironolactone suppresses aldosterone-induced Kv1.5 expression by attenuating mineralocorticoid receptor-Nox1/2/4-mediated ROS generation in neonatal rat atrial myocytes. 2019 Dec 3 1
25 31755934 Angiotensin II inhibits DDAH1-nNOS signaling via AT1R and μOR dimerization to modulate blood pressure control in the central nervous system. 2019 Dec 12 2
26 29136335 [Sar1, Ile4, Ile8]-angiotensin II Potentiates Insulin Receptor Signalling and Glycogen Synthesis in Hepatocytes. 2018 May 1
27 29167166 Blood-borne interleukin-1β acts on the subfornical organ to upregulate the sympathoexcitatory milieu of the hypothalamic paraventricular nucleus. 2018 Mar 1 1
28 29178049 AT1 receptor blockage impairs NF-κB activation mediated by thyroid hormone in cardiomyocytes. 2018 Mar 1
29 29223539 Losartan suppresses the kainate-induced changes of angiotensin AT1 receptor expression in a model of comorbid hypertension and epilepsy. 2018 Jan 15 3
30 29321548 Role and mechanism of AT1-AA in the pathogenesis of HELLP syndrome. 2018 Jan 10 1
31 29336842 Immunohistochemical localization of angiotensin AT1 receptors in the rat carotid body. 2018 Feb 3
32 29447844 Angiotensin II facilitates GABAergic neurotransmission at postsynaptic sites in rat amygdala neurons. 2018 May 1 1
33 29593122 Inhibition of AT1 receptors by losartan affects myocardial slow force response in healthy but not in monocrotaline-treated young rats. 2018 Mar 2
34 29683352 A long-lasting oral preformulation of the angiotensin II AT1 receptor antagonist losartan. 2018 Sep 3
35 29849726 Renoprotective Effect of a Chinese Herbal Formula, Qidan Dihuang Decoction, on Streptozotocin-Induced Diabetes in Rat. 2018 1
36 30422889 Combined Antihypertensive Therapies That Increase Expression of Cardioprotective Biomarkers Associated With the Renin-Angiotensin and Kallikrein-Kinin Systems. 2018 Dec 1
37 30804791 Angiotensin II-Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy. 2018 2
38 27763697 Changes in cardiovascular responses to chemoreflex activation of rats recovered from protein restriction are not related to AT1 receptors. 2017 Jan 1 1
39 28011270 H2S inhibits angiotensin II-induced atrial Kv1.5 upregulation by attenuating Nox4-mediated ROS generation during atrial fibrillation. 2017 Jan 29 1
40 28315847 Effects of peripherally and centrally applied ghrelin on the oxidative stress induced by renin angiotensin system in a rat model of renovascular hypertension. 2017 Jul 26 1
41 28483563 Losartan, a selective antagonist of AT1 receptor, attenuates seawater inhalation induced lung injury via modulating JAK2/STATs and apoptosis in rat. 2017 Aug 4
42 28542215 Treatment with enalapril and not diltiazem ameliorated progression of chronic kidney disease in rats, and normalized renal AT1 receptor expression as measured with PET imaging. 2017 1
43 28595908 Association of angiotensin II receptor 1 and lectin-like oxidized low-density lipoprotein receptor-1 mediates the cardiac hypertrophy induced by oxidized low-density lipoprotein. 2017 Aug 12 2
44 28596051 Functions of AT1 and AT2 angiotensin receptors in the paraventricular nucleus of the rat, correlating single-unit and cardiovascular responses. 2017 Jun 1
45 28625546 The lateral parabrachial nucleus and central angiotensinergic mechanisms in the control of sodium intake induced by different stimuli. 2017 Aug 30 1
46 28720883 Chronic high-sodium diet intake after weaning lead to neurogenic hypertension in adult Wistar rats. 2017 Jul 18 1
47 28851568 Angiotensin AT1 receptors modulate the anxiogenic effects of angiotensin (5-8) injected into the rat ventrolateral periaqueductal gray. 2017 Oct 1
48 28937244 Cardiac AT(1) receptor-dependent and IGF1 receptor-independent signaling is activated by a single bout of resistance exercise. 2017 Dec 20 1
49 29179208 KLF 15 Works as an Early Anti-Fibrotic Transcriptional Regulator in Ang II-Induced Renal Fibrosis via Down-Regulation of CTGF Expression. 2017 1
50 29280941 Superoxide Anions and NO in the Paraventricular Nucleus Modulate the Cardiac Sympathetic Afferent Reflex in Obese Rats. 2017 Dec 27 1