Pub. Date : 2018 Feb
PMID : 29336842
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The aim of this study was to examine the immunohistochemical localization of AT1 receptor in the CB of adult rats and to compare its expression in vehicle-treated animals, and after the long-term application of its selective blocker losartan. | Losartan | angiotensin II receptor, type 1a | Rattus norvegicus |
| 2 | Exogenous administration of losartan for a prolonged time significantly reduces the intensity of AT1 receptor immunostaining in the CB glomus cells and SCG neurons. | Losartan | angiotensin II receptor, type 1a | Rattus norvegicus |
| 3 | Our results show that AT1 receptors are largely expressed in the rat CB under physiological conditions, and their expression is down-regulated by losartan treatment. | Losartan | angiotensin II receptor, type 1a | Rattus norvegicus |