Rotenone

synuclein alpha ; Homo sapiens







89 Article(s)
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1 34984583 Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A): Could It Be a Promising Biomarker and Therapeutic Target in Parkinson's Disease? 2022 Feb 2
2 35023548 A Matrigel-based 3D construct of SH-SY5Y cells models the α-synuclein pathologies of Parkinson's disease. 2022 Mar 1 1
3 35277478 Novel anti-apoptotic L-DOPA precursors SuperDopa and SuperDopamide as potential neuroprotective agents for halting/delaying progression of Parkinson's disease. 2022 Mar 11 1
4 35457010 Autophagy Signaling by Neural-Induced Human Adipose Tissue-Derived Stem Cell-Conditioned Medium during Rotenone-Induced Toxicity in SH-SY5Y Cells. 2022 Apr 10 4
5 35471724 Correction to: Intranasal Exposure to Low-Dose Rotenone Induced Alpha-Synuclein Accumulation and Parkinson's Like Symptoms Without Loss of Dopaminergic Neurons. 2022 Jun 1
6 32086435 C/EBPβ/δ-secretase signaling mediates Parkinson's disease pathogenesis via regulating transcription and proteolytic cleavage of α-synuclein and MAOB. 2021 Feb 1
7 33552161 Therapeutic Effects of Conditioned Medium of Neural Differentiated Human Bone Marrow-Derived Stem Cells on Rotenone-Induced Alpha-Synuclein Aggregation and Apoptosis. 2021 1
8 33961406 Using Rotenone to Model Parkinson's Disease in Mice: A Review of the Role of Pharmacokinetics. 2021 May 17 2
9 34306319 LRRK2 Kinase Inhibitor Rejuvenates Oxidative Stress-Induced Cellular Senescence in Neuronal Cells. 2021 3
10 34510532 Overexpression of α-synuclein inhibits mitochondrial Ca2+ trafficking between the endoplasmic reticulum and mitochondria through MAMs by altering the GRP75-IP3R interaction. 2021 Nov 1
11 31649329 Initiation of Parkinson's disease from gut to brain by δ-secretase. 2020 Jan 1
12 31778768 Protective effect of alpha mangostin on rotenone induced toxicity in rat model of Parkinson's disease. 2020 Jan 18 1
13 32071790 Overexpression of alpha-synuclein promotes both cell proliferation and cell toxicity in human SH-SY5Y neuroblastoma cells. 2020 May 2
14 32444560 Detection and Assessment of α-Synuclein Oligomers in the Urine of Parkinson's Disease Patients. 2020 1
15 32488468 Neuroprotective Role of Quercetin on Rotenone-Induced Toxicity in SH-SY5Y Cell Line Through Modulation of Apoptotic and Autophagic Pathways. 2020 Aug 2
16 32624505 Death-associated Protein Kinase 1 Phosphorylates α-Synuclein at Ser129 and Exacerbates Rotenone-induced Toxic Aggregation of α-Synuclein in Dopaminergic SH-SY5Y Cells. 2020 Jun 30 2
17 32905883 α-Synuclein amplifies cytoplasmic peroxide flux and oxidative stress provoked by mitochondrial inhibitors in CNS dopaminergic neurons in vivo. 2020 Oct 1
18 32949572 Unique signatures of stress-induced senescent human astrocytes. 2020 Dec 2
19 33110167 Fast kinetics of environmentally induced α-synuclein aggregation mediated by structural alteration in NAC region and result in structure dependent cytotoxicity. 2020 Oct 27 1
20 33163674 Sesaminol prevents Parkinson's disease by activating the Nrf2-ARE signaling pathway. 2020 Nov 1
21 33177988 Hepcidin Decreases Rotenone-Induced α-Synuclein Accumulation via Autophagy in SH-SY5Y Cells. 2020 4
22 33469419 Ndfip1 Prevents Rotenone-Induced Neurotoxicity and Upregulation of α-Synuclein in SH-SY5Y Cells. 2020 4
23 30692508 Selective inhibition of mitochondrial sodium-calcium exchanger protects striatal neurons from α-synuclein plus rotenone induced toxicity. 2019 Jan 28 2
24 30904435 Activation of the immunoproteasome protects SH-SY5Y cells from the toxicity of rotenone. 2019 Jul 1
25 30907971 Sex Differences in Rotenone Sensitivity Reflect the Male-to-Female Ratio in Human Parkinson's Disease Incidence. 2019 Jul 1 1
26 31611767 The Impairments of α-Synuclein and Mechanistic Target of Rapamycin in Rotenone-Induced SH-SY5Y Cells and Mice Model of Parkinson's Disease. 2019 2
27 28573674 Overexpression of α-synuclein in an astrocyte cell line promotes autophagy inhibition and apoptosis. 2018 Jan 1
28 30081046 P75 Involved in the Ubiquitination of α-synuclein in Rotenone-based Parkinson's Disease Models. 2018 Sep 15 3
29 30141137 Geraniol Protects Against the Protein and Oxidative Stress Induced by Rotenone in an In Vitro Model of Parkinson's Disease. 2018 Oct 1
30 27997067 Rotenone and elevated extracellular potassium concentration induce cell-specific fibrillation of α-synuclein in axons of cholinergic enteric neurons in the guinea-pig ileum. 2017 Apr 3
31 28137648 Autophagic modulation by rosuvastatin prevents rotenone-induced neurotoxicity in an in vitro model of Parkinson's disease. 2017 Mar 6 1
32 28164279 Calcipotriol inhibits α-synuclein aggregation in SH-SY5Y neuroblastoma cells by a Calbindin-D28k-dependent mechanism. 2017 Apr 1
33 28197072 HMGB1 Mediates Autophagy Dysfunction via Perturbing Beclin1-Vps34 Complex in Dopaminergic Cell Model. 2017 2
34 28236214 Expanded and Wild-type Ataxin-3 Modify the Redox Status of SH-SY5Y Cells Overexpressing α-Synuclein. 2017 May 1
35 28417442 Mechanisms of Gene-Environment Interactions in Parkinson's Disease. 2017 Jun 1
36 28696167 Neuroprotective effect of α-mangostin on mitochondrial dysfunction and α-synuclein aggregation in rotenone-induced model of Parkinson's disease in differentiated SH-SY5Y cells. 2017 Aug 2
37 26156288 The Neuroprotective Effect of Erythropoietin on Rotenone-Induced Neurotoxicity in SH-SY5Y Cells Through the Induction of Autophagy. 2016 Aug 1
38 26826319 Neuroprotective effect of curcumin-loaded lactoferrin nano particles against rotenone induced neurotoxicity. 2016 May 1
39 27012437 The novel mechanism of rotenone-induced α-synuclein phosphorylation via reduced protein phosphatase 2A activity. 2016 Jun 4
40 27053302 SIRT3 Acts as a Neuroprotective Agent in Rotenone-Induced Parkinson Cell Model. 2016 Jul 2
41 27133439 Rotenone down-regulates HSPA8/hsc70 chaperone protein in vitro: A new possible toxic mechanism contributing to Parkinson's disease. 2016 May 3
42 27178445 Changes in the sympathetic innervation of the gut in rotenone treated mice as possible early biomarker for Parkinson's disease. 2016 Jun 1
43 25447323 Unveiling the role of the pesticides paraquat and rotenone on α-synuclein fibrillation in vitro. 2015 Jan 1
44 25665531 Involvement of mortalin/GRP75/mthsp70 in the mitochondrial impairments induced by A53T mutant α-synuclein. 2015 Apr 16 1
45 25846226 Alpha-synuclein modulates NR2B-containing NMDA receptors and decreases their levels after rotenone exposure. 2015 Jun-Jul 2
46 26363201 Differential sensitivity of immature and mature ventral mesencephalic neurons to rotenone induced neurotoxicity in vitro. 2015 Dec 25 1
47 26378986 Drugs That Bind to α-Synuclein: Neuroprotective or Neurotoxic? 2015 Dec 16 1
48 26385697 The neuroprotective role of ferrostatin-1 under rotenone-induced oxidative stress in dopaminergic neuroblastoma cells. 2015 Oct 1
49 25109238 Linking alpha-synuclein phosphorylation to reactive oxygen species formation and mitochondrial dysfunction in SH-SY5Y cells. 2014 Sep 1
50 25240592 Inhibition of prolyl oligopeptidase increases the survival of alpha-synuclein overexpressing cells after rotenone exposure by reducing alpha-synuclein oligomers. 2014 Nov 7 1