Title : Overexpression of α-synuclein inhibits mitochondrial Ca2+ trafficking between the endoplasmic reticulum and mitochondria through MAMs by altering the GRP75-IP3R interaction.

Pub. Date : 2021 Nov

PMID : 34510532






1 Functional Relationships(s)
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1 We observed that alpha-syn potentiates the mitochondrial membrane potential (Deltapsim ) loss induced by rotenone, increases mitophagy and mitochondrial Ca2+ overload. Rotenone synuclein alpha Homo sapiens