Polyphenols

synuclein alpha ; Homo sapiens







20 Article(s)
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Pub. Year
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1 33610557 Brazilin Removes Toxic Alpha-Synuclein and Seeding Competent Assemblies from Parkinson Brain by Altering Conformational Equilibrium. 2021 Apr 16 3
2 34015214 Ellagic Acid Inhibits α-Synuclein Aggregation at Multiple Stages and Reduces Its Cytotoxicity. 2021 Jun 2 1
3 34046949 Polyphenol-solubility alters amyloid fibril formation of α-synuclein. 2021 Aug 1
4 34948195 Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy. 2021 Dec 13 1
5 32822152 Potential Role of Natural Polyphenols against Protein Aggregation Toxicity: In Vitro, In Vivo, and Clinical Studies. 2020 Oct 7 1
6 33185419 Polyphenol Honokiol and Flavone 2',3',4'-Trihydroxyflavone Differentially Interact with α-Synuclein at Distinct Phases of Aggregation. 2020 Dec 16 2
7 33186020 Epigallocatechin Gallate Destabilizes α-Synuclein Fibril by Disrupting the E46-K80 Salt-Bridge and Inter-protofibril Interface. 2020 Dec 16 1
8 29976995 Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans. 2018 Jul 5 1
9 26517049 Modulating the Amyloidogenesis of α-Synuclein. 2016 1
10 25498223 Tea polyphenols alleviate motor impairments, dopaminergic neuronal injury, and cerebral α-synuclein aggregation in MPTP-intoxicated parkinsonian monkeys. 2015 Feb 12 1
11 24835632 Pitfalls associated with the use of Thioflavin-T to monitor anti-fibrillogenic activity. 2014 Jul 15 1
12 23064431 Vitamins K interact with N-terminus α-synuclein and modulate the protein fibrillization in vitro. Exploring the interaction between quinones and α-synuclein. 2013 Jan 2
13 21966584 In vitro recapitulation of aberrant protein inclusions in neurodegenerative diseases: New cellular models of neurodegenerative diseases. 2011 Jul 1
14 19895818 Characterization of inhibitor-bound alpha-synuclein dimer: role of alpha-synuclein N-terminal region in dimerization and inhibitor binding. 2010 Jan 22 1
15 20385841 EGCG remodels mature alpha-synuclein and amyloid-beta fibrils and reduces cellular toxicity. 2010 Apr 27 1
16 20801100 Amyloid formation and disaggregation of α-synuclein and its tandem repeat (α-TR). 2010 Oct 1 1
17 19183551 Inhibition of alpha-synuclein fibril assembly by small molecules: analysis using epitope-specific antibodies. 2009 Feb 18 1
18 19616561 (-)-epigallocatechin-3-gallate (EGCG) maintains kappa-casein in its pre-fibrillar state without redirecting its aggregation pathway. 2009 Sep 25 1
19 18511942 EGCG redirects amyloidogenic polypeptides into unstructured, off-pathway oligomers. 2008 Jun 1
20 16681381 Small molecule inhibitors of alpha-synuclein filament assembly. 2006 May 16 1