Title : Pitfalls associated with the use of Thioflavin-T to monitor anti-fibrillogenic activity.

Pub. Date : 2014 Jul 15

PMID : 24835632






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1 Moreover, we demonstrated that certain potent inhibitors of alpha-syn fibrillation, such as oxidized catecholamines and polyphenols, undergo spontaneous oxidation in aqueous solution, generating compounds that strongly quench ThT fluorescence. Polyphenols synuclein alpha Homo sapiens