Title : A phase I study of recombinant human interferon alpha-2b combined with 5-fluorouracil and cisplatin in patients with advanced cancer.

Pub. Date : 1995

PMID : 7882458






3 Functional Relationships(s)
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1 To determine the maximum tolerated dose (MTD) of escalating doses of interferon-alpha-2b (IFN, Intron A) with 5-fluorouracil (5-FU) and cisplatin (DDP) in patients with advanced cancer, 15 patients were accrued between May 1990 and July 1991. Fluorouracil interferon alpha 1 Homo sapiens
2 IFN was given s.c. on days 1-5 and then three times weekly with DDP (75 mg/m2, day 1) and 5-FU [750 mg/m2, days 1-5, continuous infusion (CI) on a 28-day cycle. Fluorouracil interferon alpha 1 Homo sapiens
3 The combination of IFN is possible with 5-FU and DDP. Fluorouracil interferon alpha 1 Homo sapiens