pegvisomant

insulin like growth factor 1 ; Homo sapiens







156 Article(s)
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1 35022929 Patient-reported outcomes in patients with acromegaly treated with pegvisomant in the ACROSTUDY extension: A real-world experience. 2022 Jun 2
2 35602875 Complicated Clinical Course in Incipient Gigantism Due to Treatment-resistant Aryl Hydrocarbon Receptor-Interacting Protein-mutated Pediatric Somatotropinoma. 2022 May-Jun 1
3 33295758 Enhanced Bioactivity of a Human GHR Antagonist Generated by Solid-Phase Site-Specific PEGylation. 2021 Feb 8 1
4 33553983 Body Composition Changes with Long-term Pegvisomant Therapy of Acromegaly. 2021 Mar 1 2
5 33960325 Improved AcroQoL scores in acromegaly after sagittal split ramus osteotomy with Le Fort I osteotomy. 2021 Apr 1 1
6 34342594 More than a decade of real-world experience of pegvisomant for acromegaly: ACROSTUDY. 2021 Aug 27 2
7 31917681 All-cause mortality in patients with acromegaly treated with pegvisomant: an ACROSTUDY analysis. 2020 Mar 1
8 30772778 First report on persistent remission of acromegaly after withdrawal of long-term pegvisomant monotherapy. 2019 Apr 4
9 31365626 Pituitary gigantism: a case series from Hospital de San José (Bogotá, Colombia). 2019 Jul 29 1
10 29080965 How to improve effectiveness of pegvisomant treatment in acromegalic patients. 2018 May 4
11 29155991 Efficacy and Safety of Switching to Pasireotide in Patients With Acromegaly Controlled With Pegvisomant and First-Generation Somatostatin Analogues (PAPE Study). 2018 Feb 1 1
12 29672904 Growth hormone-Insulin-like growth factor 1 axis hyperactivity on bone fibrous dysplasia in McCune-Albright Syndrome. 2018 Jul 1
13 29953972 Resistant Paediatric Somatotropinomas due to AIP Mutations: Role of Pegvisomant. 2018 3
14 27455094 Somatostatin Receptor Expression in GH-Secreting Pituitary Adenomas Treated with Long-Acting Somatostatin Analogues in Combination with Pegvisomant. 2017 4
15 27513761 The Effect of the Exon-3-Deleted Growth Hormone Receptor on Pegvisomant-Treated Acromegaly: A Systematic Review and Meta-Analysis. 2017 2
16 27631335 Pegvisomant: a growth hormone receptor antagonist used in the treatment of acromegaly. 2017 Feb 2
17 27932529 Effectiveness of first-line pegvisomant monotherapy in acromegaly: an ACROSTUDY analysis. 2017 Feb 3
18 28100630 A multivariable prediction model for pegvisomant dosing: monotherapy and in combination with long-acting somatostatin analogues. 2017 Apr 9
19 28176221 Pegvisomant in acromegaly: an update. 2017 Jun 1
20 28902627 Serum α-klotho levels are not informative for the evaluation of growth hormone secretion in short children. 2017 Oct 26 1
21 29278515 Pegvisomant-primed growth hormone (GH) stimulation test is useful in identifying true GH deficient children. 2017 Jul 1
22 30058878 Somatostatin analogs, cabergoline and pegvisomant: comparing the efficacy of medical treatment for acromegaly. 2017 Jan 1
23 26553421 Safety of long-term treatment with Pegvisomant: analysis of Spanish patients included in global ACROSTUDY. 2016 Apr 1
24 26661938 Combined treatment of somatostatin analogues with pegvisomant in acromegaly. 2016 May 1
25 26662620 Long-term treatment with pegvisomant for acromegaly: a 10-year experience. 2016 Apr 2
26 26796763 Efficacy and safety of monotherapy by pegvisomant, a growth hormone receptor antagonist, in Japanese patients with acromegaly. 2016 Apr 25 3
27 26903550 What is the efficacy of switching to weekly pegvisomant in acromegaly patients well controlled on combination therapy? 2016 May 7
28 27241667 Growth hormone receptor antagonism suppresses tumour regrowth after radiotherapy in an endometrial cancer xenograft model. 2016 Aug 28 1
29 27267119 In vitro impact of pegvisomant on growth hormone-secreting pituitary adenoma cells. 2016 Jul 4
30 27287035 Combined treatment with octreotide LAR and pegvisomant in patients with pituitary gigantism: clinical evaluation and genetic screening. 2016 Oct 1
31 27401863 Treatment with high doses of pegvisomant in 56 patients with acromegaly: experience from ACROSTUDY. 2016 Oct 3
32 27448708 Use of lanreotide in combination with cabergoline or pegvisomant in patients with acromegaly in the clinical practice: The ACROCOMB study. 2016 Oct 1
33 25712922 X-linked acrogigantism syndrome: clinical profile and therapeutic responses. 2015 Jun 1
34 25813261 [Akromegaly and pharmacotherapy]. 2015 Feb 1
35 25962899 A male patient with acromegaly and breast cancer: treating acromegaly to control tumor progression. 2015 May 12 4
36 26224528 Prediction of therapy response in acromegalic patients under pegvisomant therapy within the German ACROSTUDY cohort. 2015 Dec 1
37 26243033 Pegvisomant in combination with long-acting somatostatin analogues in acromegaly: the role of the GH receptor deletion of exon 3. 2015 Nov 5
38 26429918 Long-term effects of pegvisomant on comorbidities in patients with acromegaly: a retrospective single-center study. 2015 Nov 3
39 26596374 Pegvisomant treatment in patients with acromegaly in clinical practice: The French ACROSTUDY. 2015 Dec 3
40 23650996 Circulating levels of pegvisomant and endogenous growth hormone during prolonged pegvisomant therapy in patients with acromegaly. 2014 Jan 3
41 24035867 Evaluation of growth hormone (GH) action in mice: discovery of GH receptor antagonists and clinical indications. 2014 Apr 5 1
42 24423298 Short-term administration of pegvisomant improves hepatic insulin sensitivity and reduces soleus muscle intramyocellular lipid content in young adults with type 1 diabetes. 2014 Feb 1
43 24517150 Acromegaly and McCune-Albright syndrome. 2014 Jun 1
44 24913198 Therapy of acromegalic patients exacerbated by concomitant type 2 diabetes requires higher pegvisomant doses to normalise IGF1 levels. 2014 Jul 5
45 22396133 Pegvisomant and cabergoline combination therapy in acromegaly. 2013 Mar 1
46 23038625 Germline mutations of AIP gene in somatotropinomas resistant to somatostatin analogues. 2013 Jan 3
47 23103101 [Optimization of the medical treatment for acromegaly]. 2013 Apr 20 1
48 23337021 Control of disease activity and tumor size after introduction of pegvisomant in a lanreotide-resistant acromegalic patient. 2013 Feb 1
49 23785020 Growth hormone (GH) activity is associated with increased serum oestradiol and reduced anti-Müllerian hormone in healthy male volunteers treated with GH and a GH antagonist. 2013 Jul 1
50 30349613 Extra-hepatic Acromegaly. 2013 Mar 5