Pub. Date : 2018 May
PMID : 29080965
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PEGV was administered for up to 4 years, at doses up titrated until IGF-1 normalization or to >= 30 mg/day. | pegvisomant | insulin like growth factor 1 | Homo sapiens |
| 2 | PEGV dose was dependent on baseline IGF-1 > 2.7 x ULN (p < 0.05) and doses > 1.0 mg/BMI/day were administered more frequently when baseline IGF-1 was > 2.0 x ULN (p = 0.03). | pegvisomant | insulin like growth factor 1 | Homo sapiens |
| 3 | PEGV dose was dependent on baseline IGF-1 > 2.7 x ULN (p < 0.05) and doses > 1.0 mg/BMI/day were administered more frequently when baseline IGF-1 was > 2.0 x ULN (p = 0.03). | pegvisomant | insulin like growth factor 1 | Homo sapiens |
| 4 | Higher PEGV doses at start and a more rapid up-titration are necessary in patients with obesity and/or IGF-1 > 2.7 x ULN. | pegvisomant | insulin like growth factor 1 | Homo sapiens |