Guanosine Triphosphate

ras homolog family member A ; Homo sapiens







358 Article(s)
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1 34786954 Nitric oxide could promote development of Barrett's esophagus by S-nitrosylation-induced inhibition of Rho-ROCK signaling in esophageal fibroblasts. 2022 Jan 1 1
2 35096275 Apolipoprotein (a)/Lipoprotein(a)-Induced Oxidative-Inflammatory α7-nAChR/p38 MAPK/IL-6/RhoA-GTP Signaling Axis and M1 Macrophage Polarization Modulate Inflammation-Associated Development of Coronary Artery Spasm. 2022 1
3 35215978 Vav Proteins in Development of the Brain: A Potential Relationship to the Pathogenesis of Congenital Zika Syndrome? 2022 Feb 14 1
4 35251349 ALW-II-41-27, an EphA2 inhibitor, inhibits proliferation, migration and invasion of cervical cancer cells via inhibition of the RhoA/ROCK pathway. 2022 Apr 1
5 35294066 ArhGEF12 activates Rap1A and not RhoA in human dermal microvascular endothelial cells to reduce tumor necrosis factor-induced leak. 2022 Apr 1
6 35319996 Local temporal Rac1-GTP nadirs and peaks restrict cell protrusions and retractions. 2022 Mar 25 3
7 35497937 Crumbs3 is expressed in oral squamous cell carcinomas and promotes cell migration and proliferation by affecting RhoA activity. 2022 Jun 3
8 35583642 Targeting Cancer by Using Nanoparticles to Modulate RHO GTPase Signaling. 2022 1
9 32808262 Identification of Rho GEF and RhoA Activation by Pull-Down Assays. 2021 3
10 33421554 Expression, purification and characterization of the RhoA-binding domain of human SHIP2 in E.coli. 2021 Apr 5
11 33497604 Structure of an inactive conformation of GTP-bound RhoA GTPase. 2021 Jun 3 6
12 33588881 S-1-propenylcysteine improves TNF-α-induced vascular endothelial barrier dysfunction by suppressing the GEF-H1/RhoA/Rac pathway. 2021 Feb 15 1
13 33683574 B3GNT3 acts as a carcinogenic factor in endometrial cancer via facilitating cell growth, invasion and migration through regulating RhoA/RAC1 pathway-associated markers. 2021 May 1
14 33708809 Endothelin-1 Upregulates Activin Receptor-Like Kinase-1 Expression via Gi/RhoA/Sp-1/Rho Kinase Pathways in Human Pulmonary Arterial Endothelial Cells. 2021 3
15 33762326 The Regulatory Subunit PPP2R2A of PP2A Enhances Th1 and Th17 Differentiation through Activation of the GEF-H1/RhoA/ROCK Signaling Pathway. 2021 Apr 15 1
16 33800150 Pediatric Celiac Disease Patients Show Alterations of Dendritic Cell Shape and Actin Rearrangement. 2021 Mar 8 1
17 33825439 Nanobody-Based Quantification of GTP-Bound RHO Conformation Reveals RHOA and RHOC Activation Independent from Their Total Expression in Breast Cancer. 2021 Apr 20 3
18 33833821 ARHGEF10L Promotes Cervical Tumorigenesis via RhoA-Mediated Signaling. 2021 1
19 33836044 Effector-mediated ERM activation locally inhibits RhoA activity to shape the apical cell domain. 2021 Jun 7 2
20 33850145 EpCAM promotes endosomal modulation of the cortical RhoA zone for epithelial organization. 2021 Apr 13 2
21 34162728 Activation of Protein Tyrosine Phosphatase Receptor Type γ Suppresses Mechanisms of Adhesion and Survival in Chronic Lymphocytic Leukemia Cells. 2021 Jul 15 1
22 34304710 Regulation of Leukaemia Associated Rho GEF (LARG/ARHGEF12). 2021 Jul 25 1
23 34709522 Assembly of the Non-Canonical Myo9a-RhoGAP and RhoA·GDP Transition State Complex in the Presence of MgF3. 2021 Dec 4
24 29455593 Acute compressive stress activates RHO/ROCK-mediated cellular processes. 2020 Sep 1
25 31888991 Structure and regulation of human epithelial cell transforming 2 protein. 2020 Jan 14 2
26 32154766 ARHGEF10L expression regulates cell proliferation and migration in gastric tumorigenesis. 2020 Jul 1
27 32231403 Reactive oxygen species in cardiovascular health and disease: special references to nitric oxide, hydrogen peroxide, and Rho-kinase. 2020 Mar 1
28 32483387 Chromosomal translocation-derived aberrant Rab22a drives metastasis of osteosarcoma. 2020 Jul 3
29 32548242 A Review on the Function and Regulation of ARHGDIB/RhoGDI2 Expression Including the Hypothetical Role of ARHGDIB/RhoGDI2 Autoantibodies in Kidney Transplantation. 2020 May 1
30 32685017 Acetylation dependent functions of Rab22a-NeoF1 Fusion Protein in Osteosarcoma. 2020 1
31 32692911 The RhoA regulators Myo9b and GEF-H1 are targets of cyclic nucleotide-dependent kinases in platelets. 2020 Nov 2
32 32825648 Vascular Shutdown by Photodynamic Therapy Using Talaporfin Sodium. 2020 Aug 21 1
33 32977360 miR-30b Promotes spinal cord sensory function recovery via the Sema3A/NRP-1/PlexinA1/RhoA/ROCK Pathway. 2020 Nov 1
34 33015036 RHOAming Through the Nucleotide Excision Repair Pathway as a Mechanism of Cellular Response Against the Effects of UV Radiation. 2020 2
35 33150183 Identification of a Novel Variant of ARHGAP29 in a Chinese Family with Nonsyndromic Cleft Lip and Palate. 2020 1
36 33167372 Endocytosis and Trafficking of Heparan Sulfate Proteoglycans in Triple-Negative Breast Cancer Cells Unraveled with a Polycationic Peptide. 2020 Nov 5 1
37 33681186 Neuropeptide Y/Y5 Receptor Pathway Stimulates Neuroblastoma Cell Motility Through RhoA Activation. 2020 1
38 30536538 Galectin-3 exacerbates ox-LDL-mediated endothelial injury by inducing inflammation via integrin β1-RhoA-JNK signaling activation. 2019 Jul 1
39 30710569 Sorafenib promotes sensory conduction function recovery via miR-142-3p/AC9/cAMP axis post dorsal column injury. 2019 Apr 2
40 30783010 Structure of the C-terminal guanine nucleotide exchange factor module of Trio in an autoinhibited conformation reveals its oncogenic potential. 2019 Feb 19 4
41 30848088 Pard3 suppresses glioma invasion by regulating RhoA through atypical protein kinase C/NF-κB signaling. 2019 May 1
42 30848208 In-Silico QSAR Modelling of Predicted Rho Kinase Inhibitors Against Cardio Vascular Diseases. 2019 1
43 30959099 Tumor-secreted GRP78 facilitates the migration of macrophages into tumors by promoting cytoskeleton remodeling. 2019 Aug 3
44 31038818 A GAP-GTPase-GDP-Pi Intermediate Crystal Structure Analyzed by DFT Shows GTP Hydrolysis Involves Serial Proton Transfers. 2019 Jun 26 1
45 31105010 Anillin Promotes Cell Contractility by Cyclic Resetting of RhoA Residence Kinetics. 2019 Jun 17 4
46 31396321 Platelet-rich plasma in combination with adipose-derived stem cells promotes skin wound healing through activating Rho GTPase-mediated signaling pathway. 2019 1
47 31445161 Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation. 2019 Dec 1
48 31490066 Interconnecting Flexibility, Structural Communication, and Function in RhoGEF Oncoproteins. 2019 Oct 28 1
49 31623230 Arp2/3-Branched Actin Maintains an Active Pool of GTP-RhoA and Controls RhoA Abundance. 2019 Oct 16 2
50 28832024 Activation of RHOA-VAV1 signaling in angioimmunoblastic T-cell lymphoma. 2018 Mar 1