Guanosine Triphosphate

ras homolog family member A ; Homo sapiens







358 Article(s)
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51 29208526 LARG GEF and ARHGAP18 orchestrate RhoA activity to control mesenchymal stem cell lineage. 2018 Feb 1
52 29355776 RhoA inactivation by S-nitrosylation regulates vascular smooth muscle contractive signaling. 2018 Apr 1 5
53 29373579 An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. 2018 1
54 29377108 Regulation of RhoA GTPase and various transcription factors in the RhoA pathway. 2018 Sep 2
55 29476987 Isoprenoids and tau pathology in sporadic Alzheimer's disease. 2018 May 2
56 29555978 Sema4C/PlexinB2 signaling controls breast cancer cell growth, hormonal dependence and tumorigenic potential. 2018 Jul 1
57 29695506 A structural study of the complex between neuroepithelial cell transforming gene 1 (Net1) and RhoA reveals a potential anticancer drug hot spot. 2018 Jun 8 2
58 29717112 Gastrin stimulates pancreatic cancer cell directional migration by activating the Gα12/13-RhoA-ROCK signaling pathway. 2018 May 1 1
59 29940100 SmgGDS-607 Regulation of RhoA GTPase Prenylation Is Nucleotide-Dependent. 2018 Jul 24 4
60 30064461 Circular RNA IARS (circ-IARS) secreted by pancreatic cancer cells and located within exosomes regulates endothelial monolayer permeability to promote tumor metastasis. 2018 Jul 31 3
61 27974245 RhoA GTPase oxidation stimulates cell proliferation via nuclear factor-κB activation. 2017 Feb 1
62 28007915 Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO. 2017 Jan 2 1
63 28035042 ROCK1 but not ROCK2 contributes to RhoA signaling and NMIIA-mediated contractility at the epithelial zonula adherens. 2017 Jan 1 1
64 28386321 Acid fibroblast growth factor preserves blood-brain barrier integrity by activating the PI3K-Akt-Rac1 pathway and inhibiting RhoA following traumatic brain injury. 2017 2
65 28487984 Induction of cell cycle arrest by increasing GTP‑RhoA levels via Taxol‑induced microtubule polymerization in renal cell carcinoma. 2017 Jun 6
66 28584191 ARHGAP42 is activated by Src-mediated tyrosine phosphorylation to promote cell motility. 2017 Jul 15 1
67 28681593 5-Hydroxytryptamine 6 Receptor (5-HT6R)-Mediated Morphological Changes via RhoA-Dependent Pathways. 2017 Jul 31 2
68 28779705 Diaphanous-related formin-3 overexpression inhibits the migration and invasion of triple-negative breast cancer by inhibiting RhoA-GTP expression. 2017 Oct 2
69 29039527 Simvastatin inhibits the expression of stemness‑related genes and the metastatic invasion of human cancer cells via destruction of the cytoskeleton. 2017 Dec 1
70 29061365 Rho-specific Guanine nucleotide exchange factors (Rho-GEFs) inhibition affects macrophage phenotype and disrupts Golgi complex. 2017 Dec 2
71 29114068 Receptor tyrosine kinase activation of RhoA is mediated by AKT phosphorylation of DLC1. 2017 Dec 4 7
72 29121972 Long noncoding RNA NORAD, a novel competing endogenous RNA, enhances the hypoxia-induced epithelial-mesenchymal transition to promote metastasis in pancreatic cancer. 2017 Nov 9 2
73 29333768 [Effects of geranylgeranyltransferase Ⅰ gene silencing by RNA interference on the migration and invasion of tongue carcinoma]. 2017 Dec 1 2
74 26556565 Pathophysiological effects of RhoA and Rho-associated kinase on cardiovascular system. 2016 Jan 2
75 26574607 Variegated RHOA mutations in adult T-cell leukemia/lymphoma. 2016 Feb 4 3
76 26775587 Small GTPases in peroxisome dynamics. 2016 May 1
77 26822702 (19)F NMR and DFT Analysis Reveal Structural and Electronic Transition State Features for RhoA-Catalyzed GTP Hydrolysis. 2016 Mar 1 2
78 26825171 RASSF1A Directly Antagonizes RhoA Activity through the Assembly of a Smurf1-Mediated Destruction Complex to Suppress Tumorigenesis. 2016 Apr 1 1
79 26838319 RhoA/Rho-Kinase in the Cardiovascular System. 2016 Jan 22 1
80 26968247 Combined inhibition of the mevalonate pathway with statins and zoledronic acid potentiates their anti-tumor effects in human breast cancer cells. 2016 May 28 1
81 27216196 Rho GTPase Transcriptome Analysis Reveals Oncogenic Roles for Rho GTPase-Activating Proteins in Basal-like Breast Cancers. 2016 Jul 1 1
82 27363609 Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism. 2016 Jul 31 4
83 27376838 Nitric oxide increases the migratory activity of non-small cell lung cancer cells via AKT-mediated integrin αv and β1 upregulation. 2016 Oct 1
84 27396430 Expression of G Protein-coupled Receptor 56 Is an Unfavorable Prognostic Factor in Osteosarcoma Patients. 2016 Jul 2
85 27501997 p-Hydroxylcinnamaldehyde induces the differentiation of oesophageal carcinoma cells via the cAMP-RhoA-MAPK signalling pathway. 2016 Aug 9 2
86 27566291 Ph(-) myeloproliferative neoplasm red blood cells display deregulation of IQGAP1-Rho GTPase signaling depending on CALR/JAK2 status. 2016 Nov 1
87 27606625 Dimethyloxalylglycine Promotes Bone Marrow Mesenchymal Stem Cell Osteogenesis via Rho/ROCK Signaling. 2016 2
88 27628050 Rho GTPases: Regulation and roles in cancer cell biology. 2016 Oct 2
89 27992599 RhoA Proteolysis Regulates the Actin Cytoskeleton in Response to Oxidative Stress. 2016 1
90 25162437 Light and Dark of Reactive Oxygen Species for Vascular Function: 2014 ASVB (Asian Society of Vascular Biology). 2015 May 1
91 25174401 A novel role for Plk4 in regulating cell spreading and motility. 2015 Jun 2
92 25359885 A complex of p190RhoGAP-A and anillin modulates RhoA-GTP and the cytokinetic furrow in human cells. 2015 Jan 1 5
93 25502110 Dual regulation of tumor necrosis factor-α on myosin light chain phosphorylation in vascular smooth muscle. 2015 Mar 1 2
94 25514039 Tbx3 and Nr5α2 improve the viability of porcine induced pluripotent stem cells after dissociation into single cells by inhibiting RHO-ROCK-MLC signaling. 2015 Jan 16 1
95 25593132 Vascular smooth muscle cell phenotypic changes in patients with Marfan syndrome. 2015 Apr 1
96 25734240 Compressive stress induces dephosphorylation of the myosin regulatory light chain via RhoA phosphorylation by the adenylyl cyclase/protein kinase A signaling pathway. 2015 1
97 25961457 KANK deficiency leads to podocyte dysfunction and nephrotic syndrome. 2015 Jun 1
98 26067270 Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure. 2015 Aug 7 3
99 26103434 G17V RHOA: Genetic evidence of GTP-unbound RHOA playing a role in tumorigenesis in T cells. 2015 5
100 26195453 A High-Throughput Assay for Rho Guanine Nucleotide Exchange Factors Based on the Transcreener GDP Assay. 2015 Dec 1