Title : Identification of Rho GEF and RhoA Activation by Pull-Down Assays.

Pub. Date : 2021

PMID : 32808262






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 RhoA gets activated upon binding to guanine nucleotide exchange factors (GEFs), which catalyze the exchange of guanosine diphosphate (GDP) for guanosine triphosphate (GTP). Guanosine Triphosphate ras homolog family member A Homo sapiens
2 RhoA gets activated upon binding to guanine nucleotide exchange factors (GEFs), which catalyze the exchange of guanosine diphosphate (GDP) for guanosine triphosphate (GTP). Guanosine Triphosphate ras homolog family member A Homo sapiens
3 GTPase-activating proteins (GAPs) mediate the exchange of GTP to GDP, inactivating RhoA, whereas guanine nucleotide dissociation inhibitors (GDIs) preserve the inactive pool of RhoA proteins in the cytosol. Guanosine Triphosphate ras homolog family member A Homo sapiens