Title : MDM2 does not influence p53-mediated sensitivity to DNA-damaging drugs.

Pub. Date : 2002 Oct

PMID : 12481433






1 Functional Relationships(s)
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1 When p53 expression was induced, cells became chemosensitive to actinomycin D in the presence or absence of MDM2 expression; this result suggests that MDM2 cannot inhibit p53-mediated chemosensitivity. Dactinomycin tumor protein p53 Homo sapiens