Sulfhydryl Compounds

tumor protein p53 ; Homo sapiens







22 Article(s)
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Pub. Year
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1 33314700 A thiol-bound drug reservoir enhances APR-246-induced mutant p53 tumor cell death. 2021 Feb 5 1
2 33656867 Integrative Analysis of lncRNA-mRNA Coexpression in Human Lung Epithelial Cells Exposed to Dimethyl Selenide-Derived Secondary Organic Aerosols. 2021 Mar 15 1
3 31945496 Thiol antioxidants sensitize malabaricone C induced cancer cell death via reprogramming redox sensitive p53 and NF-κB proteins in vitro and in vivo. 2020 Feb 20 2
4 33055209 Functional interplay among thiol-based redox signaling, metabolism, and ferroptosis unveiled by a genetic variant of TP53. 2020 Oct 27 2
5 30057300 Role of Thiol Reactivity for Targeting Mutant p53. 2018 Oct 18 5
6 30318520 Mutant p53 blocks SESN1/AMPK/PGC-1α/UCP2 axis increasing mitochondrial O2-· production in cancer cells. 2018 Oct 1
7 25584637 Oxidation of p53 through DNA charge transport involves a network of disulfides within the DNA-binding domain. 2015 Jan 27 1
8 22926048 A bioactive probe of the oxidative pentose phosphate cycle: novel strategy to reverse radioresistance in glucose deprived human colon cancer cells. 2013 Feb 1
9 23354308 Degradation of NF-κB, p53 and other regulatory redox-sensitive proteins by thiol-conjugating and -nitrosylating drugs in human tumor cells. 2013 May 1
10 21117647 Interactions of apurinic/apyrimidinic endonuclease with a redox inhibitor: evidence for an alternate conformation of the enzyme. 2011 Jan 11 1
11 21472523 Identification of two reactive cysteine residues in the tumor suppressor protein p53 using top-down FTICR mass spectrometry. 2011 May 1
12 21780454 Identification of p53 gene by using CdSe/ZnS conjugation and hybridization. 2011 May 1
13 19411067 PRIMA-1 reactivates mutant p53 by covalent binding to the core domain. 2009 May 5 1
14 19633417 Mutant p53 rescue and modulation of p53 redox state. 2009 Aug 15 1
15 18025460 A role for DNA-mediated charge transport in regulating p53: Oxidation of the DNA-bound protein from a distance. 2007 Nov 27 3
16 20818013 Progressing single biomolecule force spectroscopy measurements for the screening of DNA binding agents. 2005 Oct 1
17 12527914 Thiol alkylation inhibits the mitogenic effects of platelet-derived growth factor and renders it proapoptotic via activation of STATs and p53 and induction of expression of caspase1 and p21(waf1/cip1). 2003 Jan 9 2
18 14580323 Formation of disulfide bond in p53 correlates with inhibition of DNA binding and tetramerization. 2003 Oct 5
19 10713709 The cytoprotective aminothiol WR1065 activates p21waf-1 and down regulates cell cycle progression through a p53-dependent pathway. 2000 Feb 24 1
20 10866285 Cytoprotection by WR-1065, the active form of amifostine, is independent of p53 status in human malignant glioma cell lines. 2000 May 1
21 11023973 Nitrosation and oxidation in the regulation of gene expression. 2000 Oct 1
22 8533007 Protein thiol modification and apoptotic cell death as cGMP-independent nitric oxide (NO) signaling pathways. 1996 1