Pub. Date : 2013 Feb
PMID : 22926048
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | HEDS is rapidly detoxified in normal glucose but triggered a p53-independent metabolic stress in glucose depleted state that caused loss of NADPH, protein and non-protein thiol homeostasis and Ku function, and enhanced sensitivity of both p53 wild type and mutant cells to radiation induced oxidative stress. | Sulfhydryl Compounds | tumor protein p53 | Homo sapiens |