Gefitinib

tumor protein p53 ; Homo sapiens







21 Article(s)
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1 35216325 A Transcriptomic Approach to Elucidate the Mechanisms of Gefitinib-Induced Toxicity in Healthy Human Intestinal Organoids. 2022 Feb 17 1
2 34192651 TP53 mutations in circulating tumor DNA in advanced epidermal growth factor receptor-mutant lung adenocarcinoma patients treated with gefitinib. 2021 Sep 2
3 34370268 STAT3 inhibitor BBI608 enhances the antitumor effect of gefitinib on EGFR-mutated non-small cell lung cancer cells. 2021 Nov 2
4 34445495 Gain-of-Function Mutant TP53 R248Q Overexpressed in Epithelial Ovarian Carcinoma Alters AKT-Dependent Regulation of Intercellular Trafficking in Responses to EGFR/MDM2 Inhibitor. 2021 Aug 16 3
5 34799910 P1-39: Paclitaxel induces growth inhibition in gefitinib-resistant PC9-MET cells by downregulating MDM2 and activating p53. 2021 Nov 1
6 35273907 The Landscape of Actionable Genomic Alterations by Next-Generation Sequencing in Tumor Tissue Versus Circulating Tumor DNA in Chinese Patients With Non-Small Cell Lung Cancer. 2021 1
7 32742376 TP53 mutation influences the efficacy of treatment of colorectal cancer cell lines with a combination of sirtuin inhibitors and chemotherapeutic agents. 2020 Aug 1
8 33089100 Matrix Metalloprotease-7 Mediates Nucleolar Assembly and Intra-nucleolar Cleaving p53 in Gefitinib-Resistant Cancer Stem Cells. 2020 Oct 23 2
9 31168030 The anti-cancer drug gefitinib accelerates Fas-mediated apoptosis by enhancing caspase-8 activation in cancer cells. 2019 1
10 28247504 Epigallocatechin-3-gallate augments the therapeutic effects of benzo[a]pyrene-mediated lung carcinogenesis. 2017 Jul 8 1
11 28529576 Increased MIR31HG lncRNA expression increases gefitinib resistance in non-small cell lung cancer cell lines through the EGFR/PI3K/AKT signaling pathway. 2017 May 1
12 30641628 [Effect of Fuzheng Kang'ai Recipe Combined Gefitinib on Lung Cancer A549 Cells and Its Mecha- nism Research]. 2016 Nov 1
13 25501339 Ad-p53 enhances the sensitivity of triple-negative breast cancer MDA-MB-468 cells to the EGFR inhibitor gefitinib. 2015 Feb 2
14 25623760 [Effect of recombinant human p53 adenovirus (Ad-p53) combined with EGFR inhibitor gefitinib on the sensitivity of breast cancer MDA-MB-468 cells]. 2014 Dec 4
15 21216229 Aurora-A promotes gefitinib resistance via a NF-κB signaling pathway in p53 knockdown lung cancer cells. 2011 Feb 11 8
16 21406185 Suppression of Stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells. 2011 Jun 1 2
17 18973751 An epidermal growth factor inhibitor, Gefitinib, induces apoptosis through a p53-dependent upregulation of pro-apoptotic molecules and downregulation of anti-apoptotic molecules in human lung adenocarcinoma A549 cells. 2008 Dec 14 7
18 17283151 p53 enhances gefitinib-induced growth inhibition and apoptosis by regulation of Fas in non-small cell lung cancer. 2007 Feb 1 7
19 17404024 The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses proliferation and invasion of human oral squamous carcinoma cells via p53 independent and MMP, uPAR dependent mechanism. 2007 Jan 2
20 17490733 Consequences of the loss of p53, RB1, and PTEN: relationship to gefitinib resistance in endometrial cancer. 2007 Jul 2
21 16166444 Molecular alterations in tumors and response to combination chemotherapy with gefitinib for advanced colorectal cancer. 2005 Sep 15 1