Pub. Date : 2015 Feb
PMID : 25501339
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Ad-p53 enhances the sensitivity of triple-negative breast cancer MDA-MB-468 cells to the EGFR inhibitor gefitinib. | Gefitinib | tumor protein p53 | Homo sapiens |
2 | Importantly, wild-type p53 was able to reverse the drug resistance of MDA-MB-468 cells to gefitinib through inactivation of the phosphatidylinositol 3-kinase (PI3K)/Akt pathway. | Gefitinib | tumor protein p53 | Homo sapiens |