| 1 |
34309458 | Quercetin and Luteolin Improve the Anticancer Effects of 5-Fluorouracil in Human Colorectal Adenocarcinoma In Vitro Model: A Mechanistic Insight. | 2022 |
2 |
| 2 |
35154466 | Synergistic effects of CP-25 and 5-fluorouracil on the hepatocellular carcinoma in vivo and in vitro through regulating activating mitochondrial pathway. | 2022 |
1 |
| 3 |
35191521 | ATR inhibitor AZD6738 increases the sensitivity of colorectal cancer cells to 5‑fluorouracil by inhibiting repair of DNA damage. | 2022 Apr |
1 |
| 4 |
35410287 | Single-cell analysis of p53 transitional dynamics unravels stimulus- and cell type-dependent signaling output motifs. | 2022 Apr 11 |
1 |
| 5 |
33240430 | Potentiating activities of chrysin in the therapeutic efficacy of 5-fluorouracil in gastric cancer cells. | 2021 Jan |
1 |
| 6 |
33500399 | Natural podophyllotoxin analog 4DPG attenuates EMT and colorectal cancer progression via activation of checkpoint kinase 2. | 2021 Jan 26 |
1 |
| 7 |
33564015 | Retraction Note: JNK confers 5-fluorouracil resistance in p53-deficient and mutant p53-expressing colon cancer cells by inducing survival autophagy. | 2021 Feb 9 |
2 |
| 8 |
33613715 | p53 expression confers sensitivity to 5-fluorouracil via distinct chromatin accessibility dynamics in human colorectal cancer. | 2021 Mar |
5 |
| 9 |
33662352 | Perifosine enhances the potential antitumor effect of 5-fluorourasil and oxaliplatin in colon cancer cells harboring the PIK3CA mutation. | 2021 May 5 |
2 |
| 10 |
33764853 | Temporal gene regulation by p53 is associated with the rotational setting of its binding sites in nucleosomes. | 2021 Apr |
1 |
| 11 |
33798968 | Efficient intracellular delivery of p53 protein by engineered protein crystals restores tumor suppressing function in vivo. | 2021 Apr |
3 |
| 12 |
33906076 | Tenacissoside G synergistically potentiates inhibitory effects of 5-fluorouracil to human colorectal cancer. | 2021 Jun |
1 |
| 13 |
34117917 | Anticancer activity of Helicobacter pylori ribosomal protein (HPRP) with iRGD in treatment of colon cancer. | 2021 Oct |
1 |
| 14 |
34151400 | New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids. | 2021 Aug |
1 |
| 15 |
34279763 | The role of SIRT5 and p53 proteins in the sensitivity of colon cancer cells to chemotherapeutic agent 5-Fluorouracil. | 2021 Jul |
2 |
| 16 |
34452150 | Cellulose Nanofiber-Based Hydrogels Embedding 5-FU Promote Pyroptosis Activation in Breast Cancer Cells and Support Human Adipose-Derived Stem Cell Proliferation, Opening New Perspectives for Breast Tissue Engineering. | 2021 Aug 1 |
1 |
| 17 |
34562873 | Apigenin enhances apoptosis induction by 5-fluorouracil through regulation of thymidylate synthase in colorectal cancer cells. | 2021 Nov |
1 |
| 18 |
34637097 | Quercetin potentiates the chemosensitivity of MCF-7 breast cancer cells to 5-fluorouracil. | 2021 Dec |
2 |
| 19 |
34794098 | Molecular hybridization design and synthesis of novel spirooxindole-based MDM2 inhibitors endowed with BCL2 signaling attenuation; a step towards the next generation p53 activators. | 2021 Dec |
1 |
| 20 |
34901834 | A narrative review of genetic factors affecting fluoropyrimidine toxicity. | 2021 Dec |
1 |
| 21 |
34970530 | Design, Synthesis, Chemical and Biochemical Insights Into Novel Hybrid Spirooxindole-Based p53-MDM2 Inhibitors With Potential Bcl2 Signaling Attenuation. | 2021 |
1 |
| 22 |
35071232 | Deficient or R273H and R248W Mutations of p53 Promote Chemoresistance to 5-FU via TCF21/CD44 Axis-Mediated Enhanced Stemness in Colorectal Carcinoma. | 2021 |
2 |
| 23 |
35096810 | Down-Regulating HAUS6 Suppresses Cell Proliferation by Activating the p53/p21 Pathway in Colorectal Cancer. | 2021 |
1 |
| 24 |
30693808 | Cepharanthine combined with 5-fluorouracil inhibits the growth of p53-mutant human colorectal cancer cells. | 2020 Apr |
2 |
| 25 |
31518438 | BTK inhibitors synergise with 5-FU to treat drug-resistant TP53-null colon cancers. | 2020 Feb |
2 |
| 26 |
31897925 | Management of sinonasal adenocarcinomas with anterior skull base extension. | 2020 Dec |
1 |
| 27 |
31898732 | Cooperation of SRPK2, Numb and p53 in the malignant biology and chemosensitivity of colorectal cancer. | 2020 Jan 31 |
1 |
| 28 |
31903119 | Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/MDM2 axis in colorectal cancer. | 2020 |
1 |
| 29 |
31923958 | UV-light cross-linked and pH de-cross-linked coumarin-decorated cationic copolymer grafted mesoporous silica nanoparticles for drug and gene co-delivery in vitro. | 2020 Mar |
3 |
| 30 |
31938994 | iASPP-Mediated ROS Inhibition Drives 5-Fu Resistance Dependent on Nrf2 Antioxidative Signaling Pathway in Gastric Adenocarcinoma. | 2020 Oct |
2 |
| 31 |
31969973 | Inhibition of protein FAK enhances 5-FU chemosensitivity to gastric carcinoma via p53 signaling pathways. | 2020 |
1 |
| 32 |
32194724 | Involvement of ribosomal protein L11 expression in sensitivity of gastric cancer against 5-FU. | 2020 Mar |
3 |
| 33 |
32457882 | β-Elemene Reverses the Resistance of p53-Deficient Colorectal Cancer Cells to 5-Fluorouracil by Inducing Pro-death Autophagy and Cyclin D3-Dependent Cycle Arrest. | 2020 |
5 |
| 34 |
32731241 | The Evolving Role of Systemic Therapy in the Primary Treatment of Sinonasal Cancer. | 2020 |
1 |
| 35 |
32742376 | TP53 mutation influences the efficacy of treatment of colorectal cancer cell lines with a combination of sirtuin inhibitors and chemotherapeutic agents. | 2020 Aug |
1 |
| 36 |
32782527 | Konjac glucomannan reverses multi-drug resistance of HepG2/5-FU cells by suppressing AKT signaling and increasing p53 expression. | 2020 Sep |
1 |
| 37 |
33005290 | Molecular determinants of response to 5-fluorouracil-based chemotherapy in colorectal cancer: The undisputable role of micro-ribonucleic acids. | 2020 Sep 15 |
1 |
| 38 |
33087710 | 5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation. | 2020 Oct 21 |
4 |
| 39 |
33389946 | Combined Effects of Protocatechuic Acid and 5-Fluorouracil on p53 Gene Expression and Apoptosis in Gastric Adenocarcinoma Cells. | 2020 Dec 23 |
4 |
| 40 |
30488540 | Augmented antitumor activity of 5-fluorouracil by double knockdown of MDM4 and MDM2 in colon and gastric cancer cells. | 2019 Feb |
5 |
| 41 |
30723502 | Autophagy Regulated by Gain of Function Mutant p53 Enhances Proteasomal Inhibitor-Mediated Cell Death through Induction of ROS and ERK in Lung Cancer Cells. | 2019 |
1 |
| 42 |
30770552 | Mechanism of bioactive polysaccharide from Lachnum sp. acts synergistically with 5-fluorouracil against human hepatocellular carcinoma. | 2019 Feb 15 |
1 |
| 43 |
31002510 | Fuplatin: An Efficient and Low-Toxic Dual-Prodrug. | 2019 May 9 |
1 |
| 44 |
31042625 | Epigenetically Down-Regulated Acetyltransferase PCAF Increases the Resistance of Colorectal Cancer to 5-Fluorouracil. | 2019 Jun |
1 |
| 45 |
31366086 | Lipoic Acid Synergizes with Antineoplastic Drugs in Colorectal Cancer by Targeting p53 for Proteasomal Degradation. | 2019 Jul 30 |
2 |
| 46 |
31544060 | Activation of p53 Gene Expression and Synergistic Antiproliferative Effects of 5-Fluorouracil and β-escin on MCF7 Cells. | 2019 Jul-Sep |
3 |
| 47 |
31569395 | N6-Isopentenyladenosine Inhibits Colorectal Cancer and Improves Sensitivity to 5-Fluorouracil-Targeting FBXW7 Tumor Suppressor. | 2019 Sep 28 |
1 |
| 48 |
31592435 | Synergetic Impact of Combined 5-Fluorouracil and Rutin on Apoptosis in PC3 Cancer Cells through the Modulation of P53 Gene Expression. | 2019 Aug |
3 |
| 49 |
27871087 | The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1. | 2018 |
3 |
| 50 |
29138869 | Cepharanthine exhibits a potent anticancer activity in p53-mutated colorectal cancer cells through upregulation of p21Waf1/Cip1. | 2018 Jan |
1 |