Title : New insights into the mechanisms underlying 5-fluorouracil-induced intestinal toxicity based on transcriptomic and metabolomic responses in human intestinal organoids.

Pub. Date : 2021 Aug

PMID : 34151400






1 Functional Relationships(s)
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1 Based on analysis of the differentially expressed genes, the most prominent molecular pathways affected by 5-FU included cell cycle, p53 signalling, mitochondrial ATP synthesis and apoptosis. Fluorouracil tumor protein p53 Homo sapiens