Title : The role of SIRT5 and p53 proteins in the sensitivity of colon cancer cells to chemotherapeutic agent 5-Fluorouracil.

Pub. Date : 2021 Jul

PMID : 34279763






2 Functional Relationships(s)
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1 The role of SIRT5 and p53 proteins in the sensitivity of colon cancer cells to chemotherapeutic agent 5-Fluorouracil. Fluorouracil tumor protein p53 Homo sapiens
2 Our western blot experiment results showed that while Suramin decreased SIRT5 and RSV decreased FOXO3a protein expressions significantly in HCT-116 p53 -/- cells, 5-FU decreased significantly SIRT5 and FOXO3a protein expressions in a p53 independent manner. Fluorouracil tumor protein p53 Homo sapiens