| 1 |
32705888 | Genistein Suppresses v-Src-Driven Proliferative Activity by Arresting the Cell-Cycle at G2/M through Increasing p21 Level in Src-Activated Human Gallbladder Carcinoma cells. | 2021 |
1 |
| 2 |
32276266 | Inhibition of esophageal-carcinoma cell proliferation by genistein via suppression of JAK1/2-STAT3 and AKT/MDM2/p53 signaling pathways. | 2020 Apr 10 |
3 |
| 3 |
30737644 | ERβ modulates genistein's cisplatin-enhancing activities in breast cancer MDA-MB-231 cells via P53-independent pathway. | 2019 Jun |
1 |
| 4 |
31538075 | Effects of genistein on anti-tumor activity of cisplatin in human cervical cancer cell lines. | 2019 Sep |
1 |
| 5 |
29990856 | MicroRNA-1469, a p53-responsive microRNA promotes Genistein induced apoptosis by targeting Mcl1 in human laryngeal cancer cells. | 2018 Oct |
2 |
| 6 |
27861885 | Sensitivity of TP53-Mutated Cancer Cells to the Phytoestrogen Genistein Is Associated With Direct Inhibition of Plk1 Activity. | 2017 Oct |
3 |
| 7 |
26768552 | The enhancing effect of genistein on apoptosis induced by trichostatin A in lung cancer cells with wild type p53 genes is associated with upregulation of histone acetyltransferase. | 2016 Feb 1 |
5 |
| 8 |
29282909 | [Geinsten inhibits the proliferation of VCaP castration-resistant prostate cancer cells]. | 2016 Dec |
1 |
| 9 |
26032169 | Genistein induces apoptosis by stabilizing intracellular p53 protein through an APE1-mediated pathway. | 2015 Sep |
2 |
| 10 |
26469967 | Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner. | 2015 Oct 15 |
4 |
| 11 |
25745770 | Evaluation of genistein ability to modulate CTGF mRNA/protein expression, genes expression of TGFβ isoforms and expression of selected genes regulating cell cycle in keloid fibroblasts in vitro. | 2014 Nov-Dec |
1 |
| 12 |
23686257 | Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells. | 2013 Jul |
4 |
| 13 |
22736505 | Genistein induces growth arrest and suppresses telomerase activity in brain tumor cells. | 2012 Oct |
1 |
| 14 |
22960751 | Genistein demethylates the promoter of CHD5 and inhibits neuroblastoma growth in vivo. | 2012 Nov |
1 |
| 15 |
23351311 | Genistein abrogates G2 arrest induced by curcumin in p53 deficient T47D cells. | 2012 Nov 30 |
2 |
| 16 |
21965740 | Phytoestrogens induce apoptosis via extrinsic pathway, inhibiting nuclear factor-kappaB signaling in HER2-overexpressing breast cancer cells. | 2011 Oct |
1 |
| 17 |
19777160 | Synergistic efficacy of sorafenib and genistein in growth inhibition by down regulating angiogenic and survival factors and increasing apoptosis through upregulation of p53 and p21 in malignant neuroblastoma cells having N-Myc amplification or non-amplification. | 2010 Dec |
1 |
| 18 |
19994890 | Anticancer effects of flavonoid derivatives isolated from Millettia reticulata Benth in SK-Hep-1 human hepatocellular carcinoma cells. | 2010 Jan 27 |
1 |
| 19 |
20446899 | Protein tyrosine kinase pathway-derived ROS/NO productions contribute to G2/M cell cycle arrest in evodiamine-treated human cervix carcinoma HeLa cells. | 2010 Jul |
1 |
| 20 |
20554748 | PTEN and p53 cross-regulation induced by soy isoflavone genistein promotes mammary epithelial cell cycle arrest and lobuloalveolar differentiation. | 2010 Aug |
1 |
| 21 |
20661829 | Protection of p53 wild type cells from taxol by genistein in the combined treatment of lung cancer. | 2010 |
1 |
| 22 |
19373614 | Effects of selenite and genistein on G2/M cell cycle arrest and apoptosis in human prostate cancer cells. | 2009 |
2 |
| 23 |
19732843 | Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways. | 2009 Dec |
1 |
| 24 |
18324703 | Puma is a novel target of soy isoflavone genistein but is dispensable for genistein-induced cell fate determination. | 2008 Apr |
3 |
| 25 |
18357397 | The topoisomerase II inhibitor, genistein, induces G2/M arrest and apoptosis in human malignant glioma cell lines. | 2008 Apr |
2 |
| 26 |
18431742 | Genistein mediated histone acetylation and demethylation activates tumor suppressor genes in prostate cancer cells. | 2008 Aug 1 |
1 |
| 27 |
18716605 | Genistein protects the kidney from cisplatin-induced injury. | 2008 Dec |
1 |
| 28 |
18847459 | The molecular basis of genistein-induced mitotic arrest and exit of self-renewal in embryonal carcinoma and primary cancer cell lines. | 2008 Oct 10 |
1 |
| 29 |
17404287 | A critical role for p53 in the control of NF-kappaB-dependent gene expression in TLR4-stimulated dendritic cells exposed to Genistein. | 2007 Apr 15 |
2 |
| 30 |
17406801 | Radiosensitization dependent on p53 function in bronchial carcinoma cells by the isoflavone genistein and estradiol in vitro. | 2007 Apr |
2 |
| 31 |
17727682 | Soy-derived isoflavones inhibit the growth of adult T-cell leukemia cells in vitro and in vivo. | 2007 Nov |
2 |
| 32 |
15896711 | Combination of 5-fluorouracil and genistein induces apoptosis synergistically in chemo-resistant cancer cells through the modulation of AMPK and COX-2 signaling pathways. | 2005 Jul 1 |
1 |
| 33 |
14757171 | Genistein arrests hepatoma cells at G2/M phase: involvement of ATM activation and upregulation of p21waf1/cip1 and Wee1. | 2004 Feb 15 |
2 |
| 34 |
15177039 | The isoflavonoids genistein and quercetin activate different stress signaling pathways as shown by analysis of site-specific phosphorylation of ATM, p53 and histone H2AX. | 2004 Mar 4 |
7 |
| 35 |
15659824 | Proapoptotic potentials of genistein under growth stimulation by estrogen. | 2004 Dec |
1 |
| 36 |
12767058 | Nonsteroidal anti-inflammatory drug-activated gene (NAG-1) is induced by genistein through the expression of p53 in colorectal cancer cells. | 2003 Jul 20 |
5 |
| 37 |
12767922 | P21 response to DNA damage induced by genistein and etoposide in human lung cancer cells. | 2003 Jun 13 |
3 |
| 38 |
12793003 | [Study on mechanisms of human gastric carcinoma cells apoptosis induced by genistein]. | 2003 Mar |
1 |
| 39 |
11096068 | The plant isoflavenoid genistein activates p53 and Chk2 in an ATM-dependent manner. | 2001 Feb 16 |
4 |
| 40 |
11286989 | Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21(waf/cip1), p27(kip1), and Cdc25C expression. | 2001 Apr 15 |
1 |
| 41 |
11295047 | Synergistic effects of dexamethasone and genistein on the expression of Cdk inhibitor p21WAF1/CIP1 in human hepatocellular and colorectal carcinoma cells. | 2001 May |
1 |
| 42 |
11316564 | Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: possible involvement of inhibition of survival signal transduction pathways. | 2001 May 1 |
3 |
| 43 |
11400165 | Different effects of genistein on molecular markers related to apoptosis in two phenotypically dissimilar breast cancer cell lines. | 2001 Apr 2-27 |
2 |
| 44 |
10761703 | p53-independent induction of p21 (WAF1/CIP1), reduction of cyclin B1 and G2/M arrest by the isoflavone genistein in human prostate carcinoma cells. | 2000 Feb |
3 |
| 45 |
10340389 | Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein. | 1999 May 20 |
1 |
| 46 |
10368806 | p53-independent apoptosis induced by genistein in lung cancer cells. | 1999 |
2 |
| 47 |
10427135 | Induction of apoptosis and inhibition of c-erbB-2 in MDA-MB-435 cells by genistein. | 1999 Sep |
1 |
| 48 |
10529369 | p53 down-regulates ER-responsive genes by interfering with the binding of ER to ERE. | 1999 Oct 22 |
1 |
| 49 |
11776565 | [Mechanism of growth inhibition by genistein of human breast carcinoma]. | 1999 Sep |
2 |
| 50 |
9513045 | Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by P21WAF1/CIP1 induction, G2/M arrest, and apoptosis. | 1998 Apr 1 |
2 |