Pub. Date : 2017 Oct
PMID : 27861885
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | TP53-depeleted LNCaP and NCI-H460 cells using shRNA targeting human TP53 were more sensitive to cell death by treatment of genistein. | Genistein | tumor protein p53 | Homo sapiens |
2 | TP53-depeleted LNCaP and NCI-H460 cells using shRNA targeting human TP53 were more sensitive to cell death by treatment of genistein. | Genistein | tumor protein p53 | Homo sapiens |
3 | These data suggest that genistein may be a promising anticancer drug candidate due to its inhibitory activity against Plk1 as well as EGFR and effectiveness toward cancer cells, especially those with p53-mutation. | Genistein | tumor protein p53 | Homo sapiens |