Nocodazole

tumor protein p53 ; Homo sapiens







24 Article(s)
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1 30482390 Stabilization of P/CAF, as a ubiquitin ligase toward MDM2, suppresses mitotic cell death through p53-p21 activation in HCT116 cells with SIRT2 suppression. 2019 Jan 1 4
2 30126368 Mutant TP53 G245C and R273H promote cellular malignancy in esophageal squamous cell carcinoma. 2018 Aug 20 1
3 25762091 p53 target gene Rap2B regulates the cytoskeleton and inhibits cell spreading. 2015 Oct 1
4 21559451 Nocodazole treatment decreases expression of pluripotency markers Nanog and Oct4 in human embryonic stem cells. 2011 Apr 29 1
5 21708134 Phosphorylation of NDRG1 is temporally and spatially controlled during the cell cycle. 2011 Jul 29 1
6 21821009 Persistent expression of Nqo1 by p62-mediated Nrf2 activation facilitates p53-dependent mitotic catastrophe. 2011 Aug 26 1
7 22022534 Elimination of proliferating cells unmasks the shift from senescence to quiescence caused by rapamycin. 2011 1
8 19332559 TTK/hMps1 mediates the p53-dependent postmitotic checkpoint by phosphorylating p53 at Thr18. 2009 Jun 1
9 19934326 Heat shock factor 1-mediated aneuploidy requires a defective function of p53. 2009 Dec 15 2
10 18400748 The kinetics of p53 activation versus cyclin E accumulation underlies the relationship between the spindle-assembly checkpoint and the postmitotic checkpoint. 2008 Jun 6 1
11 16319535 ATM is activated by default in mitosis, localizes at centrosomes and monitors mitotic spindle integrity. 2006 Jan 2
12 16687915 Prolonged mitosis versus tetraploid checkpoint: how p53 measures the duration of mitosis. 2006 May 1
13 16945015 Quantitative characterization of mitosis-blocked tetraploid cells using high content analysis. 2006 Aug 1
14 17015431 A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization. 2006 Oct 1 2
15 12860987 Phosphorylation site interdependence of human p53 post-translational modifications in response to stress. 2003 Sep 26 2
16 14583461 Loss of p53 has site-specific effects on histone H3 modification, including serine 10 phosphorylation important for maintenance of ploidy. 2003 Oct 15 2
17 11841447 p53-mediated downregulation of Chk1 abrogates the DNA damage-induced G2M checkpoint in K562 cells, resulting in increased apoptosis. 2002 Feb 1
18 12221076 Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells. 2002 Nov 15 9
19 11244509 Increased p53 phosphorylation after microtubule disruption is mediated in a microtubule inhibitor- and cell-specific manner. 2001 Jan 4 4
20 11313973 Mechanism of hyperploid cell formation induced by microtubule inhibiting drug in glioma cell lines. 2001 Jan 25 3
21 11376010 p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle. 2001 Jun 1 3
22 9840938 Prevention of mammalian DNA reduplication, following the release from the mitotic spindle checkpoint, requires p53 protein, but not p53-mediated transcriptional activity. 1998 Nov 26 2
23 8521385 Microtubule-active drugs taxol, vinblastine, and nocodazole increase the levels of transcriptionally active p53. 1995 Dec 15 3
24 8416202 Increased expression of p34cdc2 and its kinase activity in human gastric and colonic carcinomas. 1993 Jan 2 1