| 1 |
34610339 | Malignant transformation of human bronchial epithelial cells induced by benzo [a] pyrene suggests a negative feedback of TP53 to PPP1R13L via binding a possible enhancer element. | 2021 Nov 1 |
1 |
| 2 |
34690024 | Polycyclic aromatic hydrocarbons regulate the pigmentation pathway and induce DNA damage responses in keratinocytes, a process driven by systemic immunity. | 2021 Nov |
1 |
| 3 |
32588678 | Mapping the Mitochondrial Regulation of Epigenetic Modifications in Association With Carcinogenic and Noncarcinogenic Polycyclic Aromatic Hydrocarbon Exposure. | 2020 Sep/Oct |
1 |
| 4 |
28374118 | Structural Insight into the Mechanism of Dibenzo[a,l]pyrene and Benzo[a]pyrene-Mediated Cell Proliferation Using Molecular Docking Simulations. | 2018 Dec |
4 |
| 5 |
29471073 | The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cells. | 2018 Apr 1 |
1 |
| 6 |
28247504 | Epigallocatechin-3-gallate augments the therapeutic effects of benzo[a]pyrene-mediated lung carcinogenesis. | 2017 Jul 8 |
2 |
| 7 |
28882572 | Identification of essential transcription factors for adequate DNA damage response after benzo(a)pyrene and aflatoxin B1 exposure by combining transcriptomics with functional genomics. | 2017 Sep 1 |
1 |
| 8 |
25398514 | Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism. | 2016 Feb |
2 |
| 9 |
25995008 | The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice. | 2016 Apr |
5 |
| 10 |
24798859 | Regulation of p53-targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma. | 2015 Oct |
2 |
| 11 |
26400171 | Base damage, local sequence context and TP53 mutation hotspots: a molecular dynamics study of benzo[a]pyrene induced DNA distortion and mutability. | 2015 Oct 30 |
2 |
| 12 |
24246761 | Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway. | 2014 Jan 25 |
1 |
| 13 |
24361490 | Differentiation of human placental BeWo cells by the environmental contaminant benzo(a)pyrene. | 2014 Mar 5 |
7 |
| 14 |
24362009 | Cell cycle changes mediated by the p53/miR-34c axis are involved in the malignant transformation of human bronchial epithelial cells by benzo[a]pyrene. | 2014 Mar 3 |
17 |
| 15 |
24664296 | Curcumin and vitamin E protect against adverse effects of benzo[a]pyrene in lung epithelial cells. | 2014 |
2 |
| 16 |
24736433 | p53 modulates Hsp90 ATPase activity and regulates aryl hydrocarbon receptor signaling. | 2014 Jun |
2 |
| 17 |
24868967 | [Roles of p53 in the interaction of p21 and cell cycle proteins induced by benzo [a] pyrene]. | 2014 Mar |
2 |
| 18 |
24954032 | PCB153, TCDD and estradiol compromise the benzo[a]pyrene-induced p53-response via FoxO3a. | 2014 Aug 5 |
6 |
| 19 |
21887816 | Classification of polycyclic aromatic hydrocarbons based on mutagenicity in lung tissue through DNA microarray. | 2013 Nov |
1 |
| 20 |
22410783 | Carcinogen-specific mutational and epigenetic alterations in INK4A, INK4B and p53 tumour-suppressor genes drive induced senescence bypass in normal diploid mammalian cells. | 2013 Jan 10 |
1 |
| 21 |
23703817 | BaP-induced DNA damage initiated p53-independent necroptosis via the mitochondrial pathway involving Bax and Bcl-2. | 2013 Dec |
3 |
| 22 |
20862736 | Benzo(a)pyrene induces p73 mRNA expression and necrosis in human lung adenocarcinoma H1299 cells. | 2012 Mar |
2 |
| 23 |
22227536 | In vitro malignant transformation of human bronchial epithelial cells induced by benzo(a)pyrene. | 2012 Mar |
1 |
| 24 |
22319594 | Benzo[a]pyrene, aflatoxine B₁ and acetaldehyde mutational patterns in TP53 gene using a functional assay: relevance to human cancer aetiology. | 2012 |
2 |
| 25 |
21457773 | Characterization of human breast cancer cell lines for the studies on p53 in chemical carcinogenesis. | 2011 Aug |
6 |
| 26 |
21911080 | Benzo(a)pyrene-induced mitochondrial dysfunction and cell death in p53-null Hep3B cells. | 2011 Nov 27 |
1 |
| 27 |
22044530 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin's suppression of 1-nitropyrene-induced p53 expression is mediated by cytochrome P450 1A1. | 2011 Dec 19 |
2 |
| 28 |
20371965 | Malondialdehyde-modified low density lipoprotein (MDA-LDL)-induced cell growth was suppressed by polycyclic aromatic hydrocarbons (PAHs). | 2010 Apr |
1 |
| 29 |
20596254 | CYP1A1 gene polymorphisms as a risk factor for pterygium. | 2010 Jun 9 |
3 |
| 30 |
20700368 | An association between BPDE-like DNA adduct levels and CYP1A1 and GSTM1 polymorphisma in pterygium. | 2010 Apr 8 |
2 |
| 31 |
20840854 | Non-dioxin-like PCBs interact with benzo[a]pyrene-induced p53-responses and inhibit apoptosis. | 2010 Dec 1 |
4 |
| 32 |
19027820 | Cyclin A is essential for the p53-modulated inhibition from benzo(a)pyrene toxicity in A549 cells. | 2009 Feb 4 |
3 |
| 33 |
19397966 | Induction of PUMA-alpha and down-regulation of PUMA-beta expression is associated with benzo(a)pyrene-induced apoptosis in MCF-7 cells. | 2009 Aug 10 |
5 |
| 34 |
17932951 | Anti-diol epoxide of benzo[a]pyrene induces transient Mdm2 and p53 Ser15 phosphorylation, while anti-diol epoxide of dibenzo[a,l]pyrene induces a nontransient p53 Ser15 phosphorylation. | 2008 Apr |
1 |
| 35 |
17942461 | Identification through microarray gene expression analysis of cellular responses to benzo(a)pyrene and its diol-epoxide that are dependent or independent of p53. | 2008 Jan |
6 |
| 36 |
17998932 | Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72. | 2008 Apr 24 |
1 |
| 37 |
18096571 | Mdm2 as a sensitive and mechanistically informative marker for genotoxicity induced by benzo[a]pyrene and dibenzo[a,l]pyrene. | 2008 Apr |
2 |
| 38 |
18406507 | MAPK regulate p53-dependent cell death induced by benzo[a]pyrene: involvement of p53 phosphorylation and acetylation. | 2008 May 21 |
2 |
| 39 |
18440733 | Benzo(a)pyrene increases phosphorylation of p53 at serine 392 in relation to p53 induction and cell death in MCF-7 cells. | 2008 May 30 |
3 |
| 40 |
18448277 | Benzo(a)pyrene-caused increased G1-S transition requires the activation of c-Jun through p53-dependent PI-3K/Akt/ERK pathway in human embryo lung fibroblasts. | 2008 May 30 |
1 |
| 41 |
18646516 | [Overexpression and higher phosphorylation of p53 induced by benzo(a) pyrene through activated protein 1 independent pathway]. | 2008 May |
2 |
| 42 |
18788085 | Induction of centrosome amplification and chromosome instability in p53-deficient lung cancer cells exposed to benzo[a]pyrene diol epoxide (B[a]PDE). | 2008 Nov |
1 |
| 43 |
19035040 | [Effects of p53 in benzo (a) pyrene induced p21 and E2F-1 expression and cell cycle changes]. | 2008 Jun |
1 |
| 44 |
17678638 | Effects of the environmental mammary carcinogen 6-nitrochrysene on p53 and p21(Cip1) protein expression and cell cycle regulation in MCF-7 and MCF-10A cells. | 2007 Oct 20 |
1 |
| 45 |
16926039 | Benzopyrene exposure disrupts DNA methylation and growth dynamics in breast cancer cells. | 2006 Nov 1 |
3 |
| 46 |
17026772 | Malignant potential of intrahepatic biliary papillomatosis: a case report and review of the literature. | 2006 Oct 7 |
1 |
| 47 |
17029827 | Benzo[a]pyrene-induced DNA damage and p53 modulation in human hepatoma HepG2 cells for the identification of potential biomarkers for PAH monitoring and risk assessment. | 2006 Nov 1 |
9 |
| 48 |
15625077 | HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage. | 2005 Mar |
1 |
| 49 |
15705463 | The p53 tumour suppressor gene and the tobacco industry: research, debate, and conflict of interest. | 2005 Feb 5-11 |
1 |
| 50 |
15805253 | p53 mutations in benzo(a)pyrene-exposed human p53 knock-in murine fibroblasts correlate with p53 mutations in human lung tumors. | 2005 Apr 1 |
2 |