epigallocatechin gallate

tumor protein p53 ; Homo sapiens







59 Article(s)
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1 35548580 EGCG Inhibits Proliferation and Induces Apoptosis Through Downregulation of SIRT1 in Nasopharyngeal Carcinoma Cells. 2022 3
2 33579943 EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction. 2021 Feb 12 8
3 33906321 Epigallocatechin Gallate Enhances Inhibition Effect of DDP on the Proliferation of Gastric Cancer BGC-823 Cells by Regulating p19Arf-p53-p21Cip1 Signaling Pathway. 2021 Apr 1 3
4 33918387 Distinct Classes of Flavonoids and Epigallocatechin Gallate, Polyphenol Affects an Oncogenic Mutant p53 Protein, Cell Growth and Invasion in a TNBC Breast Cancer Cell Line. 2021 Apr 2 1
5 34590505 Genetic Interpretation of the Impacts of Honokiol and EGCG on Apoptotic and Self-Renewal Pathways in HEp-2 Human Laryngeal CD44high Cancer Stem Cells. 2021 Sep 30 2
6 34799573 Identification of ligand binding sites in intrinsically disordered proteins with a differential binding score. 2021 Nov 19 2
7 34944489 (-)-Epigallocatechin-3-Gallate Diminishes Intra-and Extracellular Amyloid-Induced Cytotoxic Effects on Cholinergic-like Neurons from Familial Alzheimer's Disease PSEN1 E280A. 2021 Dec 8 1
8 34945706 Green Tea (Camellia sinensis) Extract Induces p53-Mediated Cytotoxicity and Inhibits Migration of Breast Cancer Cells. 2021 Dec 20 4
9 31797597 Modulation of p53 Transactivation Domain Conformations by Ligand Binding and Cancer-Associated Mutations. 2020 1
10 32990229 [Epigallocatechin gallate induces CHD5 gene demethylation to promote acute myeloid leukemia cell apoptosis in vitro by regulating p19Arf-p53-p21Cip1 signaling pathway]. 2020 Sep 30 3
11 33425912 EGCG Enhanced the Anti-tumor Effect of Doxorubicine in Bladder Cancer via NF-κB/MDM2/p53 Pathway. 2020 4
12 30456590 Epigallocatechin gallate suppresses premature senescence of preadipocytes by inhibition of PI3K/Akt/mTOR pathway and induces senescent cell death by regulation of Bax/Bcl-2 pathway. 2019 Apr 1
13 31029907 Epigallocatechin gallate prevents mitochondrial impairment and cell apoptosis by regulating miR-30a/p53 axis. 2019 Aug 5
14 29656126 Epigallocatechin-3-gallate protects Kuruma shrimp Marsupeneaus japonicus from white spot syndrome virus and Vibrio alginolyticus. 2018 Jul 1
15 29940201 Epigallocatechin gallate improves insulin resistance in HepG2 cells through alleviating inflammation and lipotoxicity. 2018 Aug 1
16 30513211 The Effect of Different Treatments of (-)-Epigallocatechin-3-Gallate on Colorectal Carcinoma Cell Lines. 2018 Oct 1
17 30636605 The Sumoylation Modulated Tumor Suppressor p53 Regulates Cell Cycle Checking Genes to Mediate Lens Differentiation. 2018 1
18 28247504 Epigallocatechin-3-gallate augments the therapeutic effects of benzo[a]pyrene-mediated lung carcinogenesis. 2017 Jul 8 3
19 28927122 Mechanism of EGCG promoting apoptosis of MCF-7 cell line in human breast cancer. 2017 Sep 6
20 29955703 Genistein Prevents BRCA1 CpG Methylation and Proliferation in Human Breast Cancer Cells with Activated Aromatic Hydrocarbon Receptor. 2017 Jun 1
21 27498709 Epigallocatechin-3-gallate prevents oxidative stress-induced cellular senescence in human mesenchymal stem cells via Nrf2. 2016 Oct 3
22 27765354 Anti-cancer effect of (-)-epigallocatechin-3-gallate (EGCG) in head and neck cancer through repression of transactivation and enhanced degradation of β-catenin. 2016 Nov 15 1
23 24798859 Regulation of p53-targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma. 2015 Oct 2
24 25625511 EGCG inhibits proliferation, invasiveness and tumor growth by up-regulation of adhesion molecules, suppression of gelatinases activity, and induction of apoptosis in nasopharyngeal carcinoma cells. 2015 Jan 23 1
25 25759589 Epigallocatechin-3-gallate suppresses cell proliferation and promotes apoptosis and autophagy in oral cancer SSC-4 cells. 2015 1
26 25849487 Dual targeted therapy with p53 siRNA and Epigallocatechingallate in a triple negative breast cancer cell model. 2015 2
27 24712372 EGCG enhances the efficacy of cisplatin by downregulating hsa-miR-98-5p in NSCLC A549 cells. 2014 1
28 24847310 Effects of physiological levels of the green tea extract epigallocatechin-3-gallate on breast cancer cells. 2014 3
29 23017582 Expression of NSAID-activated gene-1 by EGCG in head and neck cancer: involvement of ATM-dependent p53 expression. 2013 Jun 3
30 23483203 Epigallocatechin gallate promotes p53 accumulation and activity via the inhibition of MDM2-mediated p53 ubiquitination in human lung cancer cells. 2013 May 12
31 23808158 [(-)-Epigallocatechin gallate regulates expression of apoptotic genes and protects cultured human lens epithelial cells under hyperglycemia]. 2013 Mar-Apr 2
32 24065519 EGCG suppresses Fused Toes Homolog protein through p53 in cervical cancer cells. 2013 Oct 3
33 24179522 Pro-apoptotic and migration-suppressing potential of EGCG, and the involvement of AMPK in the p53-mediated modulation of VEGF and MMP-9 expression. 2013 Nov 12
34 22552582 Green tea polyphenols increase p53 transcriptional activity and acetylation by suppressing class I histone deacetylases. 2012 Jul 11
35 22573016 (-)-Epigallocatechin-3-gallate (EGCG) attenuates functional deficits and morphological alterations by diminishing apoptotic gene overexpression in skeletal muscles after sciatic nerve crush injury. 2012 Aug 1
36 23251091 Combining the chemotherapeutic effects of epigallocatechin 3-gallate with siRNA-mediated p53 knock-down results in synergic pro-apoptotic effects. 2012 2
37 23259030 Preventive effects of epigallocatechin-3-O-gallate against replicative senescence associated with p53 acetylation in human dermal fibroblasts. 2012 3
38 20963498 Apoptosis of human fibrosarcoma HT-1080 cells by epigallocatechin-3-O-gallate via induction of p53 and caspases as well as suppression of Bcl-2 and phosphorylated nuclear factor-κB. 2011 Jan 3
39 19781850 EGCG induces apoptosis in human laryngeal epidermoid carcinoma Hep2 cells via mitochondria with the release of apoptosis-inducing factor and endonuclease G. 2010 Apr 1 2
40 20444544 p53-Dependent p21-mediated growth arrest pre-empts and protects HCT116 cells from PUMA-mediated apoptosis induced by EGCG. 2010 Oct 28 10
41 19406223 Identification of epigallocatechin-3-gallate in green tea polyphenols as a potent inducer of p53-dependent apoptosis in the human lung cancer cell line A549. 2009 Aug 5
42 19662644 EGCG inhibits protein synthesis, lipogenesis, and cell cycle progression through activation of AMPK in p53 positive and negative human hepatoma cells. 2009 Sep 10
43 18492823 Dietary flavonoids differentially reduce oxidized LDL-induced apoptosis in human endothelial cells: role of MAPK- and JAK/STAT-signaling. 2008 Jun 2
44 18519674 Protein phosphatase-2A is a target of epigallocatechin-3-gallate and modulates p53-Bak apoptotic pathway. 2008 Jun 1 9
45 17624304 The green tea component EGCG inhibits RNA polymerase III transcription. 2007 Sep 7 1
46 16506813 Green tea polyphenol epigallocatechin-3-gallate protects cells against peroxynitrite-induced cytotoxicity: modulatory effect of cellular G6PD status. 2006 Mar 8 1
47 17080554 Effect of epigallocatechingallate on ultraviolet B-induced photo-damage in keratinocyte cell line. 2006 1
48 15657356 Epigallocatechin-3-gallate induces apoptosis in estrogen receptor-negative human breast carcinoma cells via modulation in protein expression of p53 and Bax and caspase-3 activation. 2005 Jan 2
49 15764647 Ablation of either p21 or Bax prevents p53-dependent apoptosis induced by green tea polyphenol epigallocatechin-3-gallate. 2005 May 9
50 15795422 (-)Epigallocatechin gallate and quercetin enhance survival signaling in response to oxidant-induced human endothelial apoptosis. 2005 Apr 2